急性后部眼弓形体病：光学相干断层扫描血管造影和染料血管造影研究。
Acute Posterior Ocular Toxoplasmosis: An Optical Coherence Tomography Angiography and Dye Angiography Study.
机构信息
Eye Clinic, Department of Biomedical and Clinical Science "Luigi Sacco," Luigi Sacco Hospital, University of Milan, Milan, Italy.
Eye Institute, Cleveland Clinic Abu Dhabi, Al Maryah Island, Abu Dhabi, UAE.
出版信息
Ocul Immunol Inflamm. 2022 Apr 3;30(3):541-545. doi: 10.1080/09273948.2021.1977831. Epub 2021 Oct 12.
PURPOSE
To compare Indocyanine Green (ICGA) and fundus fluorescein angiography (FFA) with Optical Coherence Tomography Angiography (OCTA) findings in toxoplasmic chorioretinitis (TCR).
METHODS
Patients affected by active TCR were included. FFA, ICGA, and OCTA images were analyzed and lesions were compared between different modalities. Satellite dark dots (SDD) were compared between modalities.
RESULTS
Fifteen patients were enrolled. The mean lesion area was similar between fundus photography (FP), FFA, and OCTA-Retina. The mean lesion area was similar between ICGA and OCTA-Choroid slab. ICGA and OCTA-Choroid showed a larger extension of the lesion compared to FP, FFA, and OCTA-Retina ( = .01, 0.0001, and 0.0002 for ICG angiography and = .03, 0.008, and 0.0002 for OCTA-Choroid, respectively). On OCTA B-scans, the retinal flow defects were smaller than the underlying choroidal non-perfusion. The number of SDD was similar between ICGA and OCTA.
CONCLUSIONS
OCTA is a reliable method to assess retinal and choroidal involvement in TCR. OCTA confirmed a wider involvement of the choroid than the retina.
目的
比较眼内吲哚菁绿（ICGA）和眼底荧光血管造影（FFA）与光相干断层扫描血管造影（OCTA）在弓形体脉络膜视网膜炎（TCR）中的发现。
方法
纳入患有活动性 TCR 的患者。分析 FFA、ICGA 和 OCTA 图像，并比较不同模式下的病变。比较不同模式之间的卫星暗点（SDD）。
结果
共纳入 15 例患者。眼底照相（FP）、FFA 和 OCTA-Retina 之间的平均病变面积相似。ICGA 和 OCTA-Choroid 板之间的平均病变面积相似。与 FP、FFA 和 OCTA-Retina 相比，ICGA 和 OCTA-Choroid 显示病变的扩展更大（ICGA 分别为 =.01、0.0001 和 0.0002，OCTA-Choroid 为 =.03、0.008 和 0.0002）。在 OCTA B 扫描上，视网膜血流缺损小于下方脉络膜无灌注。ICGA 和 OCTA 之间的 SDD 数量相似。
结论
OCTA 是评估 TCR 视网膜和脉络膜受累的可靠方法。OCTA 证实脉络膜受累比视网膜更广泛。
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