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单侧急性弓形体性脉络膜视网膜炎伴发白色斑点样脉络膜累及的吲哚青绿血管造影研究

Unilateral Acute Macular Toxoplasmic Chorioretinitis Associated with White Dot-Like Choroidal Involvement Demonstrated on Indocyanine Green Angiography.

机构信息

Dokuz Eylül University Faculty of Medicine, Department of Ophthalmology, İzmir, Turkey.

University of Health Sciences Turkey, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.

出版信息

Turk J Ophthalmol. 2020 Aug 26;50(4):248-251. doi: 10.4274/tjo.galenos.2020.93636.

Abstract

A 9-year-old otherwise healthy boy was examined due to a 4-day history of visual decline in his right eye. Ophthalmological examination revealed an area of active retinochoroiditis in the right macula. Indocyanine green angiography (ICGA) demonstrated multiple hypocyanescent dots surrounding the active lesion extending 360 degrees towards the equator. Optical coherence tomography angiography (OCTA) exhibited dark dots on the choriocapillaris slab over areas corresponding to the hypocyanescent dots detected with ICGA. Full systemic examination and laboratory investigations were carried out. serology was positive. The diagnosis of toxoplasmic chorioretinitis with white dot-like choroidal involvement was made. Trimethoprim/sulfamethoxazole, azithromycin, and oral prednisolone were administered orally. On repeated ICGA 2 weeks later, the scattered hypocyanescent dots were significantly fewer in number. A month later, right visual acuity was improved, the macular chorioretinitis focus had become inactive, an epiretinal membrane had formed, and the dark dots on the choriocapillaris slab of OCTA were markedly diminished. ICGA may be helpful to observe possible, subtle choroidal involvement in patients with toxoplasmic chorioretinitis.

摘要

一名 9 岁健康男孩,因右眼视力下降 4 天就诊。眼科检查发现右眼黄斑区有活动性视网膜脉络膜炎。吲哚菁绿血管造影(ICGA)显示围绕活动性病变的多个弱荧光点,向赤道方向延伸 360 度。光学相干断层扫描血管造影(OCTA)显示在与 ICGA 检测到的弱荧光点相对应的脉络膜毛细血管层上有暗点。进行了全面的全身检查和实验室检查。血清学检查阳性。诊断为弓形体脉络膜视网膜炎伴白点样脉络膜受累。给予复方磺胺甲噁唑、阿奇霉素和口服泼尼松龙。2 周后重复 ICGA 时,散在的弱荧光点数量明显减少。一个月后,右眼视力提高,黄斑脉络膜视网膜炎病灶活动停止,形成视网膜前膜,OCTA 脉络膜毛细血管层上的暗点明显减少。ICGA 可能有助于观察弓形体脉络膜视网膜炎患者可能存在的细微脉络膜受累。

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