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应用纹理和分形维数分析评估龈下牙骨质表面的生物相容性

Application of Texture and Fractal Dimension Analysis to Evaluate Subgingival Cement Surfaces in Terms of Biocompatibility.

作者信息

Skośkiewicz-Malinowska Katarzyna, Mysior Martyna, Rusak Agnieszka, Kuropka Piotr, Kozakiewicz Marcin, Jurczyszyn Kamil

机构信息

Department of Conservative Dentistry with Endodontics, Wroclaw Medical University, 50-425 Wroclaw, Poland.

SCTT Academic Dental Polyclinic, 50-425 Wroclaw, Poland.

出版信息

Materials (Basel). 2021 Oct 7;14(19):5857. doi: 10.3390/ma14195857.

Abstract

Biocompatibility is defined as "the ability of a biomaterial, prosthesis, or medical device to perform with an appropriate host response in a specific application". Biocompatibility is especially important for restorative dentists as they use materials that remain in close contact with living tissues for a long time. The research material involves six types of cement used frequently in the subgingival region: Ketac Fil Plus (3M ESPE, Germany), Riva Self Cure (SDI, Australia) (Glass Ionomer Cements), Breeze (Pentron Clinical, USA) (Resin-based Cement), Adhesor Carbofine (Pentron, Czech Republic), Harvard Polycarboxylat Cement (Harvard Dental, Great Britain) (Zinc polycarboxylate types of cement) and Agatos S (Chema-Elektromet, Poland) (Zinc Phosphate Cement). Texture and fractal dimension analysis was applied. An evaluation of cytotoxicity and cell adhesion was carried out. The fractal dimension of Breeze (Pentron Clinical, USA) differed in each of the tested types of cement. Adhesor Carbofine (Pentron, Czech Republic) cytotoxicity was rated 4 on a 0-4 scale. The Ketac Fil Plus (3M ESPE, Germany) and Riva Self Cure (SDI, Australia) cements showed the most favorable conditions for the adhesion of fibroblasts, despite statistically significant differences in the fractal dimension of their surfaces.

摘要

生物相容性被定义为“生物材料、假体或医疗器械在特定应用中与宿主产生适当反应的能力”。生物相容性对修复牙医尤为重要,因为他们使用的材料会长时间与活组织紧密接触。研究材料包括六种在龈下区域常用的黏固剂:Ketac Fil Plus(德国3M ESPE公司)、Riva Self Cure(澳大利亚SDI公司)(玻璃离子黏固剂)、Breeze(美国Pentron Clinical公司)(树脂基黏固剂)、Adhesor Carbofine(捷克共和国Pentron公司)、哈佛聚羧酸锌黏固剂(英国哈佛牙科公司)(聚羧酸锌类黏固剂)以及Agatos S(波兰Chema-Elektrom公司)(磷酸锌黏固剂)。应用了纹理和分形维数分析。进行了细胞毒性和细胞黏附评估。Breeze(美国Pentron Clinical公司)的分形维数在每种测试的黏固剂类型中都有所不同。Adhesor Carbofine(捷克共和国Pentron公司)的细胞毒性在0 - 4级评分中为4级。Ketac Fil Plus(德国3M ESPE公司)和Riva Self Cure(澳大利亚SDI公司)黏固剂对成纤维细胞黏附显示出最有利的条件,尽管它们表面的分形维数存在统计学上的显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6c7/8510438/ae9afcaf4bb2/materials-14-05857-g001.jpg

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