Izidoro Catarina, Botelho João, Machado Vanessa, Reis Ana Mafalda, Proença Luís, Alves Ricardo, Mendes José João
Periodontology Department, Egas Moniz Dental Clinic (EMDC), Egas Moniz-Cooperativa de Ensino Superior, 2829-511 Almada, Portugal.
Clinical Research Unit (CRU), Egas Moniz Interdisciplinary Research Center (CiiEM), Egas Moniz-Cooperativa de Ensino Superior, 2829-511 Almada, Portugal.
J Clin Med. 2021 Sep 26;10(19):4415. doi: 10.3390/jcm10194415.
We aimed to explore the association between volatile sulfurous compounds (VSCs) and periodontal epithelial surface area (PESA) and periodontal inflamed surface area (PISA) on a cohort of periodontitis patients. Consecutive patients were assessed for periodontitis and halitosis. A full-mouth periodontal status assessment tested probing depth (PD), clinical attachment loss (CAL), gingival recession (REC), bleeding on probing (BoP), PISA and PESA. A halitosis assessment was made using a VSC detector device. Periodontal measures were regressed across VSC values using adjusted multivariate linear analysis. From a total of seventy-two patients (37 females/35 males), the PESA of posterior-lower regions was found to be significantly higher in halitosis cases than their non-halitosis counterparts ( = 0.031). Considering all patients, the PESA of the posterior-lower region (B = 1.3, 95% CI: 0.2-2.3, = 0.026) and age (B = -1.6, 95% CI: -3.1-0.2, = 0.026) showed significant association with VSCs. In halitosis patients, the PESA of the posterior-lower region (B = 0.1, 95% CI: 0.0-0.1, = 0.001), PISA Total (B = -0.1, 95% CI: -0.1-0.0, = 0.008) and the OHIP-14 domain of physical disability (B = -2.1, 95% CI:-4.1-0.1, = 0.040) were the most significant variables in this model. The PESA from the posterior-lower region may be associated with VSCs when other causes of extra-oral halitosis are excluded. Further intervention studies are needed to confirm this association.
我们旨在探讨一组牙周炎患者中挥发性含硫化合物（VSCs）与牙周上皮表面积（PESA）及牙周炎症表面积（PISA）之间的关联。对连续的患者进行牙周炎和口臭评估。全口牙周状况评估检测探诊深度（PD）、临床附着丧失（CAL）、牙龈退缩（REC）、探诊出血（BoP）、PISA和PESA。使用VSC检测装置进行口臭评估。采用调整后的多变量线性分析，将牙周测量指标与VSC值进行回归分析。在总共72名患者（37名女性/35名男性）中，发现口臭患者下颌后部区域的PESA显著高于无口臭患者（P = 0.031）。考虑所有患者，下颌后部区域的PESA（B = 1.3，95%置信区间：0.2 - 2.3，P = 0.026）和年龄（B = -1.6，95%置信区间：-3.1 - 0.2，P = 0.026）与VSCs显示出显著关联。在口臭患者中，下颌后部区域的PESA（B = 0.1，95%置信区间：0.0 - 0.1，P = 0.001）、总PISA（B = -0.1，95%置信区间：-0.1 - 0.0，P = 0.008）以及口腔健康影响程度量表14项（OHIP - 14）中身体残疾领域（B = -2.1，95%置信区间：-4.1 - 0.1，P = 0.040）是该模型中最显著的变量。排除其他口外口臭原因后，下颌后部区域来源的PESA可能与VSCs相关。需要进一步的干预研究来证实这种关联。
