Clin Nephrol. 2021 Dec;96(6):309-316. doi: 10.5414/CN109806.
Develop a novel chronic kidney disease (CKD)-specific stress scale and examine associations with patient characteristics.
Adults with CKD stages 1 - 5 enrolled in a cross-sectional survey. Eight questions assessed patients' thoughts and feelings of stress related to CKD (CKD Stress Scale). Patients also reported their knowledge of CKD, barriers to CKD health, and demographics. The scale was evaluated using exploratory factor analysis and Cronbach's alpha. Associations were examined via linear regression.
245 participant enrolled with a mean age of 60 years and a mean estimated glomerular filtration rate (eGFR) of 34 mL/min/1.73m; 49% were women (match percentage in Table 1), 74% White, 14% African American. A one-factor model of CKD Stress exhibited high internal consistency (α = 0.89). In bivariate analyses, higher CKD Stress was associated with lower eGFR, younger age, African American race (compared to White), and having a high school education or some college (compared to college degree or higher). Adjusting for these characteristics, as well as income and knowledge about CKD, only lower eGFR (b = -0.01; 95% CI [-0.01, -0.001]), younger age (b = -0.01; 95% CI [-0.01, -0.003]), African American race (b = 0.35, 95% CI [0.10, 0.60]), and receiving a high school education or some college (b = 0.20, 95% CI [0.01, 0.39]) were independently associated with more CKD-specific stress. Concurrent validity was supported by associations between stress and perceived barriers to care.
Our CKD Stress Scale exhibits excellent internal reliability and identified where future educational interventions may benefit from tailoring for at-risk patients.
开发一种新的慢性肾脏病(CKD)特异性应激量表,并研究其与患者特征的相关性。
纳入了 1-5 期 CKD 患者参与横断面调查。8 个问题评估了患者与 CKD 相关的思想和感受压力(CKD 应激量表)。患者还报告了他们对 CKD 的了解、CKD 健康障碍以及人口统计学特征。通过探索性因子分析和 Cronbach's alpha 对量表进行评估。通过线性回归检验相关性。
245 名参与者平均年龄为 60 岁,平均估算肾小球滤过率(eGFR)为 34ml/min/1.73m2;49%为女性(表 1 中为匹配百分比),74%为白人,14%为非裔美国人。CKD 应激的单因素模型表现出较高的内部一致性(α=0.89)。在双变量分析中,较高的 CKD 应激与较低的 eGFR、较年轻的年龄、非裔美国人种族(与白人相比)以及具有高中或大专学历(与本科或更高学历相比)相关。在调整这些特征以及收入和对 CKD 的了解后,只有较低的 eGFR(b=-0.01;95%CI[-0.01,-0.001])、较年轻的年龄(b=-0.01;95%CI[-0.01,-0.003])、非裔美国人种族(b=0.35;95%CI[0.10,0.60])和接受高中或大专教育(b=0.20;95%CI[0.01,0.39])与更多的 CKD 特异性应激相关。通过应激与护理障碍的感知之间的关联,支持了该量表的同时效度。
我们的 CKD 应激量表具有良好的内部可靠性,并确定了未来的教育干预可能需要针对高危患者进行调整的地方。