Roux-en-Y 胃旁路术与袖状胃切除术治疗超级肥胖症的比较：系统评价和荟萃分析。
Roux-en-Y Gastric Bypass Vs Sleeve Gastrectomy in Super Obesity: a Systematic Review and Meta-Analysis.
机构信息
Faculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal.
Obesity Integrated Responsibility Unit (CRI-O), São João University Medical Center, 4099-001, Porto, Portugal.
出版信息
Obes Surg. 2022 Jan;32(1):170-185. doi: 10.1007/s11695-021-05745-8. Epub 2021 Oct 12.
Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are safe procedures that may present sub-optimal results in superobesity (SO). A meta-analysis was performed aiming to summarize the available evidence on weight loss (primary outcome) and comorbidities resolution of LRYGB and LSG in patients with SO (BMI ≥ 50 kg/m). From the 16 included studies, 7 integrated the meta-analysis. LRYGB showed a significantly higher weight loss at 6 to 12-months, but not after 24 months and a higher dyslipidemia resolution at 12 months. When compared with LSG, LRYGB achieved better weight loss after 6 and 12 months and higher dyslipidemia resolution after 1 year. There were no significant differences for resolution of the other co-morbidities studied.
腹腔镜 Roux-en-Y 胃旁路术（LRYGB）和腹腔镜袖状胃切除术（LSG）是安全的手术，但在超级肥胖（SO）患者中可能无法获得理想的效果。本 meta 分析旨在总结 LRYGB 和 LSG 在 SO 患者（BMI≥50kg/m）中减轻体重（主要结局）和解决合并症的现有证据。在纳入的 16 项研究中，有 7 项研究进行了 meta 分析。LRYGB 在 6 至 12 个月时的减重效果明显更高，但在 24 个月后并无差异，在 12 个月时血脂异常的改善更为显著。与 LSG 相比，LRYGB 在术后 6 个月和 12 个月时的减重效果更好，在术后 1 年时血脂异常的改善更为显著。对于其他研究的合并症，LRYGB 和 LSG 之间没有显著差异。
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