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大型城市基于消防的 EMS 系统中院前低滴度 O 型阳性全血的管理。

Stewardship of Prehospital Low Titer O-Positive Whole Blood in a Large Urban Fire-Based EMS System.

出版信息

Prehosp Emerg Care. 2022 Nov-Dec;26(6):848-854. doi: 10.1080/10903127.2021.1992052. Epub 2021 Nov 22.

Abstract

Trauma is the leading cause of death for those aged 1 to 46 years with most fatalities resulting from hemorrhage prior to arrival to hospital. Hemorrhagic shock patients receiving transfusion with 15 minutes experience lower mortality. Prehospital blood transfusion has many legal, fiduciary, and logistical issues. The San Antonio Fire Department participates in a consortium designed to enhance the stewardship of prehospital whole blood. This study aimed to stratify blood usage amongst the field supervisors and special operations units that carry whole blood. This was a 12-month retrospective analysis of blood usage. Blood tracking forms (used for either blood exchange of transfusion) were cross referenced with city financial records to determine blood usage patterns in the 7th Largest City in the US. We used descriptive statistics, compared usage ratios, and chi-square to compare dichotomized data. A total of 363 whole blood units were obtained and 248 (68.3%) units of whole blood were transfused. EMS field supervisors transfused 74% of whole blood vs. 44% for special operations ambulances (p= <0.001). Response vehicles located in densely populated areas had the highest usage rates. All blood units were either transfused or returned for a zero blood unit wastage for expiration. The information contained within this work can provide other EMS agencies with a basic framework for comparison. The data from the SAFD's whole blood transfusion rate coupled with the clinical transfusion guideline has provided some insight for prospective agencies considering adopting a whole blood program. EMS systems and municipalities with similar characteristics can project their own whole blood needs and make informed decisions regarding program feasibility and design.

摘要

创伤是 1 至 46 岁人群死亡的主要原因,大多数死亡发生在到达医院前的出血。在 15 分钟内接受输血的失血性休克患者死亡率较低。院前输血存在许多法律、信托和后勤问题。圣安东尼奥消防局参与了一个旨在加强院前全血管理的联盟。本研究旨在对携带全血的现场主管和特种作战单位的血液使用情况进行分层。这是一项为期 12 个月的回顾性血液使用分析。血液追踪表(用于血液交换或输血)与城市财务记录交叉参考,以确定美国第七大城市的血液使用模式。我们使用描述性统计数据、比较使用率比以及卡方检验来比较二分类数据。共获得 363 单位全血,其中 248 单位(68.3%)全血用于输血。EMS 现场主管输注了 74%的全血,而特种作战救护车仅输注了 44%(p<0.001)。位于人口密集地区的响应车辆使用率最高。所有血液单位均已输注或因过期而退回,无零血液单位浪费。本工作中的信息可以为其他 EMS 机构提供比较的基本框架。SAFD 的全血输血率数据加上临床输血指南,为正在考虑采用全血计划的未来机构提供了一些见解。具有类似特征的 EMS 系统和市政当局可以预测自己的全血需求,并就计划的可行性和设计做出明智的决策。

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