Deutsch E
Fortschr Med. 1978 Apr 13;96(14):761-2.
A review of the pathogenesis of thrombocytopenias is given. The various types of thrombocytopenia are classified according to the main pathogenetic mechanisms such as reduced platelet production, increased platelet destruction and disturbed platelet distribution by splenic pooling. Finally thrombocytopenia by artefacts is discussed such as platelet satillitism and spontaneous aggregation. In the second part of the paper the differential diagnosis of several forms of thrombocytopenic purpura is presented.
本文对血小板减少症的发病机制进行了综述。根据主要发病机制,如血小板生成减少、血小板破坏增加以及脾脏池化导致的血小板分布紊乱,对各种类型的血小板减少症进行了分类。最后讨论了假性血小板减少症,如血小板卫星现象和自发性聚集。在本文的第二部分,介绍了几种形式的血小板减少性紫癜的鉴别诊断。