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一位年轻的显微镜下多血管炎患者,需要进行血液透析,且由于不同病因,反复发作可能与后部可逆性脑病综合征相关的并发症。

A Young Patient with Microscopic Polyangiitis Requiring Hemodialysis with Complications of Repeated Episodes of Posterior Reversible Encephalopathy Syndrome Probably Due to Different Etiologies.

机构信息

Department of Internal Medicine, Teikyo University School of Medicine, Japan.

出版信息

Intern Med. 2022 May 1;61(9):1423-1431. doi: 10.2169/internalmedicine.7941-21. Epub 2021 Oct 12.

Abstract

A young woman with microscopic polyangiitis (MPA) requiring hemodialysis showed repeated posterior reversible encephalopathy syndrome (PRES) with spatiotemporal multiple lesions over a period of two months. The first PRES episode with confusion and the second PRES episode with vertigo and nausea were caused by MPA, hypertension and renal failure. These symptoms were improved by the reinforcement of MPA treatment and blood pressure management. The third PRES episode with nausea, headache, seizure and visual changes was induced by rituximab infusion and hypertension. The PRES was improved with blood pressure and convulsant management. These conditions are challenging to diagnose and treat.

摘要

一位患有显微镜下多血管炎(MPA)需要血液透析的年轻女性在两个月的时间内反复发作伴有时空多发病变的后部可逆性脑病综合征(PRES)。第一次 PRES 发作伴有意识模糊,第二次 PRES 发作伴有眩晕和恶心,由 MPA、高血压和肾衰竭引起。这些症状通过强化 MPA 治疗和血压管理得到改善。第三次 PRES 发作伴有恶心、头痛、癫痫发作和视力改变,由利妥昔单抗输注和高血压引起。通过血压和抗惊厥药物管理改善 PRES。这些情况的诊断和治疗具有挑战性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3add/9152853/fc75bd61ba43/1349-7235-61-1423-g001.jpg

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