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放射性血管肉瘤表现为大量胸腔积液。

Radiation-associated Angiosarcoma Presenting as Massive Pleural Effusion.

机构信息

Department of Respiratory Medicine and Rheumatology, Graduate School of Biomedical Sciences, Tokushima University, Japan.

Department of Thoracic, Endocrine Surgery and Oncology, Graduate School of Biomedical Sciences, Tokushima University, Japan.

出版信息

Intern Med. 2022 May 1;61(9):1393-1397. doi: 10.2169/internalmedicine.8195-21. Epub 2021 Oct 12.

DOI:10.2169/internalmedicine.8195-21
PMID:34645765
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9152858/
Abstract

A 67-year-old man was admitted to our hospital for massive pleural effusion. He had a history of mandibular gingival carcinoma treated with radiation therapy (RT). Based on the cytology findings of pleural effusion and a thoracoscopic pleural biopsy, we finally diagnosed him with radiation-associated angiosarcoma. Retrospective cell-block immunocytochemistry with pleural effusion also showed potential utility for the diagnosis. This case highlights the importance of considering the possibility of radiation-associated secondary cancer in patients with pleural effusion who have a history of RT.

摘要

一位 67 岁男性因大量胸腔积液被收入我院。他患有下颌牙龈癌,曾接受过放射治疗(RT)。根据胸腔积液的细胞学检查结果和胸腔镜胸膜活检,我们最终诊断为放射性血管肉瘤。胸腔积液细胞块免疫细胞化学回顾性检查也显示出对诊断有潜在的作用。本病例强调了在有 RT 病史的胸腔积液患者中,考虑放射性相关继发性癌症的可能性的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e52/9152858/ed85a51c0219/1349-7235-61-1393-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e52/9152858/0710cc7f3035/1349-7235-61-1393-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e52/9152858/ba4fb236064d/1349-7235-61-1393-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e52/9152858/2bf6af7c855b/1349-7235-61-1393-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e52/9152858/f8d7022ab908/1349-7235-61-1393-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e52/9152858/ed85a51c0219/1349-7235-61-1393-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e52/9152858/0710cc7f3035/1349-7235-61-1393-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e52/9152858/ba4fb236064d/1349-7235-61-1393-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e52/9152858/2bf6af7c855b/1349-7235-61-1393-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e52/9152858/f8d7022ab908/1349-7235-61-1393-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e52/9152858/ed85a51c0219/1349-7235-61-1393-g005.jpg

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本文引用的文献

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Epithelioid angiosarcoma: A rare cause of pericarditis and pleural effusion.上皮样血管肉瘤:心包炎和胸腔积液的罕见病因。
Respir Med Case Rep. 2018 Apr 20;24:77-80. doi: 10.1016/j.rmcr.2018.04.008. eCollection 2018.
2
Primary Splenic Angiosarcoma with Liver Metastasis: A Rare Neoplasm Diagnosed on Fine-needle Aspiration Cytology and Cell Block Immunocytochemistry.原发性脾血管肉瘤伴肝转移:经细针穿刺抽吸细胞学检查及细胞块免疫细胞化学诊断的罕见肿瘤
J Cytol. 2018 Apr-Jun;35(2):114-116. doi: 10.4103/JOC.JOC_148_16.
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Radiation-induced Angiosarcoma as a Cause of Pleural Effusion.
放射性血管肉瘤——复发性胸腔积液的罕见病因。
Respirol Case Rep. 2024 Sep 9;12(9):e70013. doi: 10.1002/rcr2.70013. eCollection 2024 Sep.
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Am J Respir Crit Care Med. 2017 Aug 15;196(4):e10-e11. doi: 10.1164/rccm.201702-0442IM.
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Pazopanib in advanced vascular sarcomas: an EORTC Soft Tissue and Bone Sarcoma Group (STBSG) retrospective analysis.帕唑帕尼治疗晚期血管肉瘤:一项欧洲癌症研究与治疗组织软组织和骨肉瘤组(STBSG)的回顾性分析。
Acta Oncol. 2017 Jan;56(1):88-92. doi: 10.1080/0284186X.2016.1234068. Epub 2016 Nov 14.
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