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眼内和围手术期多剂量滴眼液的污染。

Contamination of multi dose eyedrops in the intra and perioperative context.

机构信息

Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

Department of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

出版信息

Sci Rep. 2021 Oct 13;11(1):20364. doi: 10.1038/s41598-021-99892-8.

DOI:10.1038/s41598-021-99892-8
PMID:34645913
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8514486/
Abstract

In this study, we examined the rate of contamination of multi-dose ophthalmic solutions in the operating theatre and the underlying risk for infection by examining the microbiological load on the tips of the dispenser bottles. A total of 245 samples of eye drop bottles were collected and analysed between June 2018 and January 2019. All were collected in the operating theatre of the University Eye Hospital Hamburg-Eppendorf. Contamination of the dropper tip occurred in 2% of the samples. Although the prevalence of contamination was low, the results of this study reveal the possibility of contamination of multi-dose eyedrops even when used by health care professionals in the controlled environment of an operating theatre. Following these results, we recommend the use of single-dose eyedrops in the pre- and intraoperative context.

摘要

在这项研究中,我们通过检查分配器瓶尖端的微生物负荷,检查了手术室中多剂量眼科溶液的污染率以及感染的潜在风险。2018 年 6 月至 2019 年 1 月期间共收集和分析了 245 个滴眼液瓶样本。所有样本均在汉堡-埃彭多夫大学眼科医院的手术室收集。在 2%的样本中发现了滴头污染。尽管污染的发生率很低,但这项研究的结果表明,即使在手术室受控环境中由医护人员使用,多剂量滴眼剂也存在污染的可能性。根据这些结果,我们建议在术前和术中使用单剂量滴眼剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a83/8514486/7d7c64623672/41598_2021_99892_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a83/8514486/7d7c64623672/41598_2021_99892_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a83/8514486/7d7c64623672/41598_2021_99892_Fig1_HTML.jpg

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