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伤寒继发的大量胃肠道出血

Massive Gastrointestinal Hemorrhage Secondary to Typhoid Fever.

作者信息

Aamer Sameen, Ahmed Sara, Ahmed Khakan, Iqbal Nadeem

机构信息

Internal Medicine, Shifa International Hospital Islamabad, Islamabad, PAK.

Medicine, Shifa International Hospital Islamabad, Islamabad, PAK.

出版信息

Cureus. 2021 Aug 30;13(8):e17552. doi: 10.7759/cureus.17552. eCollection 2021 Aug.

Abstract

Typhoid fever is caused by , a gram-negative organism. The disease usually presents with high-grade fever, abdominal pain, and diarrhea. Gastrointestinal hemorrhage is a frequent complication of the disease. However, adequate treatment with antibiotics has lowered the rate of complications. We present the case of a 21-year-old male who was admitted to the hospital with high-grade fever and per rectal bleeding. A few hours after admission, the patient had episodes of massive per rectal bleeding which resulted in hemodynamic instability. The bleeding was then successfully controlled with endoscopic hemoclipping. Concurrently, his blood culture results showed growth of for which antibiotic therapy was initiated, and the patient's condition improved thereafter. This report highlights the rare occurrence of massive lower gastrointestinal bleeding in patients with typhoid fever. It also signifies the use of endoscopic therapy with endoclips for the management of massive lower gastrointestinal bleeding.

摘要

伤寒热由一种革兰氏阴性菌引起。该疾病通常表现为高热、腹痛和腹泻。胃肠道出血是该疾病常见的并发症。然而,使用抗生素进行充分治疗已降低了并发症的发生率。我们报告一例21岁男性病例,该患者因高热和直肠出血入院。入院后数小时,患者出现大量直肠出血,导致血流动力学不稳定。随后通过内镜下止血夹成功控制了出血。同时,他的血培养结果显示[此处原文缺失具体细菌名称]生长,因此开始了抗生素治疗,此后患者病情有所改善。本报告强调了伤寒热患者罕见的大量下消化道出血情况。它还表明了使用内镜下止血夹治疗大量下消化道出血的方法。

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Massive Gastrointestinal Hemorrhage Secondary to Typhoid Fever.伤寒继发的大量胃肠道出血
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本文引用的文献

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Antibiotic Resistance and Typhoid.抗生素耐药性与伤寒。
Clin Infect Dis. 2019 Mar 7;68(Suppl 2):S165-S170. doi: 10.1093/cid/ciy1111.
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Massive Lower Gastrointestinal Bleed caused by Typhoid Ulcer: Conservative Management.伤寒溃疡导致的大量下消化道出血:保守治疗
Euroasian J Hepatogastroenterol. 2017 Jul-Dec;7(2):176-177. doi: 10.5005/jp-journals-10018-1242. Epub 2017 Sep 29.
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Multidrug-resistant typhoid fever: a review.多重耐药性伤寒热:综述
J Infect Dev Ctries. 2011 May 28;5(5):324-37. doi: 10.3855/jidc.1405.
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Global trends in typhoid and paratyphoid Fever.全球伤寒和副伤寒流行趋势。
Clin Infect Dis. 2010 Jan 15;50(2):241-6. doi: 10.1086/649541.

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