Poschner Thomas, Werner Paul, Kocher Alfred, Laufer Guenther, Musumeci Francesco, Andreas Martin, Russo Marco
Department of Cardiac Surgery, Medical University Vienna, Vienna, Austria.
Department of Cardiac Surgery & Heart Transplantation, San Camillo Forlanini Hospital of Rome, Rome, Italy.
Future Cardiol. 2022 Feb;18(2):101-113. doi: 10.2217/fca-2021-0065. Epub 2021 Oct 14.
Transcatheter aortic valve replacement is a valuable alternative technique to surgery and the spectrum of therapy continues to evolve. The JenaValve Pericaridal transcatheter aortic valve replacement System allows prosthesis fixation in a native, noncalcified aortic annulus with a unique paper clip-like anchorage mechanism. The low rate of paravalvular leakage and permanent pacemaker implantation emphasizes the further widespread use of the JenaValve - despite the limited data available. In May 2021, a CE mark for the transfemoral implantation in both aortic regurgitation and aortic stenosis was granted. However, no data have been published so far. The ongoing ALIGN trials are expected to provide the pending long-term data.
经导管主动脉瓣置换术是一种有价值的替代手术技术，治疗范围仍在不断发展。耶拿瓣膜心包经导管主动脉瓣置换系统通过独特的回形针状锚固机制，可将假体固定在天然的、无钙化的主动脉瓣环中。瓣周漏和永久性起搏器植入率低，这凸显了耶拿瓣膜将得到更广泛应用——尽管现有数据有限。2021年5月，该系统经股动脉植入治疗主动脉反流和主动脉狭窄获得了CE标志。然而，目前尚未发表相关数据。正在进行的ALIGN试验有望提供尚未获得的长期数据。
