J Am Vet Med Assoc. 2021 Nov 1;259(9):1032-1039. doi: 10.2460/javma.259.9.1032.
To establish a pathoepidemiological model to evaluate the role of SARS-CoV-2 infection in the first 10 companion animals that died while infected with SARS-CoV-2 in the US.
10 cats and dogs that tested positive for SARS-CoV-2 and died or were euthanized in the US between March 2020 and January 2021.
A standardized algorithm was developed to direct case investigations, determine the necessity of certain diagnostic procedures, and evaluate the role, if any, that SARS-CoV-2 infection played in the animals' course of disease and death. Using clinical and diagnostic information collected by state animal health officials, state public health veterinarians, and other state and local partners, this algorithm was applied to each animal case.
SARS-CoV-2 was an incidental finding in 8 animals, was suspected to have contributed to the severity of clinical signs leading to euthanasia in 1 dog, and was the primary reason for death for 1 cat.
This report provides the global community with a standardized process for directing case investigations, determining the necessity of certain diagnostic procedures, and determining the clinical significance of SARS-CoV-2 infections in animals with fatal outcomes and provides evidence that SARS-CoV-2 can, in rare circumstances, cause or contribute to death in pets.
建立一个病理流行病学模型，以评估在美国感染 SARS-CoV-2 的前 10 只死亡伴侣动物中 SARS-CoV-2 感染的作用。
2020 年 3 月至 2021 年 1 月期间在美国感染 SARS-CoV-2 后检测呈阳性并死亡或被安乐死的 10 只猫和狗。
制定了一个标准化算法来指导病例调查，确定某些诊断程序的必要性，并评估 SARS-CoV-2 感染在动物疾病过程和死亡中的作用（如果有）。利用州动物卫生官员、州公共卫生兽医以及其他州和地方合作伙伴收集的临床和诊断信息，将该算法应用于每个动物病例。
SARS-CoV-2 在 8 只动物中是偶然发现的，1 只狗被怀疑其感染导致临床症状加重而被安乐死，1 只猫的主要死因是 SARS-CoV-2 感染。
本报告为全球社区提供了一个标准化流程，用于指导病例调查、确定某些诊断程序的必要性以及确定具有致命结局的动物中 SARS-CoV-2 感染的临床意义，并提供了证据表明 SARS-CoV-2 在极少数情况下可导致宠物死亡或促使其死亡。
