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60岁以上患者移位髋臼骨折单纯切开复位内固定与切开复位内固定加全髋关节置换术的比较:一项前瞻性临床试验

Open reduction and internal fixation alone versus open reduction and internal fixation plus total hip arthroplasty for displaced acetabular fractures in patients older than 60 years: A prospective clinical trial.

作者信息

Manson Theodore T, Slobogean Gerard P, Nascone Jason W, Sciadini Marcus F, LeBrun Christopher T, Boulton Christina L, O'Hara Nathan N, Pollak Andrew N, O'Toole Robert V

机构信息

From the R Adams Cowley Shock Trauma Center, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore MD, United States.

From the R Adams Cowley Shock Trauma Center, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore MD, United States.

出版信息

Injury. 2022 Feb;53(2):523-528. doi: 10.1016/j.injury.2021.09.048. Epub 2021 Oct 2.

Abstract

INTRODUCTION

The optimal treatment of elderly patients with an acetabular fracture is unknown. We conducted a prospective clinical trial to compare functional outcomes and reoperation rates in patients older than 60 years with acetabular fracture treated with open reduction and internal fixation (ORIF) alone versus ORIF plus concomitant total hip arthroplasty (ORIF + THA). Our hypothesis was that patients who had ORIF + THA would have better patient reported outcomes and lower reoperation rates postoperatively.

METHODS

Inclusion criteria were patients older than 60 years with acetabular fracture plus at least one of three fracture characteristics: dome impaction, femoral head fracture, or posterior wall component. Eligible patients were operative candidates based on fracture displacement, ambulatory status, and physiological appropriateness. Patients received either ORIF alone or ORIF + THA (accomplished at same surgery through same incision). Outcome measurements included Western Ontario and McMaster Universities Osteoarthritis Index hip score, Short Form 36, Harris Hip Score, and Patient Satisfaction Questionnaire Short Form scores. Additionally, patients were monitored for any unplanned reoperation within 2 years.

RESULTS

Forty-seven of 165 eligible patients with an average age of 70.7 years were included. The mean Harris Hip Score difference favored ORIF + THA (mean difference, 12.3, [95% confidence interval (CI), -0.3 to 24.9, p = 0.07]). No clinically important differences were detected in any other validated outcome score or patient satisfaction score 1 year after surgery. ORIF + THA decreased the absolute risk of reoperation by 28% (95% CI, 13% to 44%, p < 0.01). No postoperative hip dislocation occurred in either group.

CONCLUSIONS

In patients older than 60 years with an operative displaced acetabular fracture with specific fracture features (dome impaction, femoral head fracture, or posterior wall component), treatment with ORIF + THA resulted in fewer reoperations than treatment with ORIF alone. No differences in patient satisfaction and other validated outcome measures were detected.

摘要

引言

老年髋臼骨折患者的最佳治疗方法尚不清楚。我们进行了一项前瞻性临床试验,比较60岁以上髋臼骨折患者单纯切开复位内固定术(ORIF)与ORIF联合同期全髋关节置换术(ORIF + THA)的功能结局和再次手术率。我们的假设是,接受ORIF + THA治疗的患者术后患者报告结局更好,再次手术率更低。

方法

纳入标准为60岁以上髋臼骨折患者,且具备以下三种骨折特征中的至少一种:髋臼顶撞击、股骨头骨折或后壁骨折块。符合条件的患者根据骨折移位情况、活动状态和生理适应性确定为手术候选者。患者接受单纯ORIF或ORIF + THA治疗(通过相同切口在同一手术中完成)。结局指标包括西安大略和麦克马斯特大学骨关节炎指数髋关节评分、简明健康状况调查量表、Harris髋关节评分和患者满意度问卷简表评分。此外,对患者进行为期2年的任何非计划性再次手术监测。

结果

165例符合条件的患者中,平均年龄70.7岁的47例被纳入研究。平均Harris髋关节评分差异有利于ORIF + THA(平均差异为12.3,[95%置信区间(CI),-0.3至24.9,p = 0.07])。术后1年,在任何其他经过验证的结局评分或患者满意度评分中均未检测到具有临床意义的差异。ORIF + THA使再次手术的绝对风险降低了28%(95%CI,13%至44%,p < 0.01)。两组均未发生术后髋关节脱位。

结论

对于60岁以上有移位的髋臼骨折且具有特定骨折特征(髋臼顶撞击、股骨头骨折或后壁骨折块)的患者,与单纯ORIF治疗相比,ORIF + THA治疗导致的再次手术更少。在患者满意度和其他经过验证的结局指标方面未检测到差异。

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