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国家免疫咨询委员会(NACI)2021 - 2022年季节性流感疫苗声明摘要。

Summary of the National Advisory Committee on Immunization (NACI) Seasonal Influenza Vaccine Statement for 2021-2022.

出版信息

Can Commun Dis Rep. 2021 Sep 10;47(9):372-380. doi: 10.14745/ccdr.v47i09a04.

DOI:10.14745/ccdr.v47i09a04
PMID:34650334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8448463/
Abstract

BACKGROUND

Several influenza vaccines are authorized in Canada and the evidence on influenza immunization is continually evolving. The National Advisory Committee on Immunization (NACI) provides recommendations regarding the use of seasonal influenza vaccines annually to the Public Health Agency of Canada (PHAC).

OBJECTIVE

To summarize NACI recommendations regarding the use of seasonal influenza vaccines for 2021-2022 and to highlight new recommendations.

METHODS

Annual influenza vaccine recommendations are developed by NACI's Influenza Working Group for consideration and approval by NACI. The development of the recommendations is based on the NACI evidence-based process.

RESULTS

The following new recommendations were made: 1) Influvac Tetra may be considered as an option among the standard dose quadrivalent inactivated influenza vaccines (IIV4-SD) offered to adults and children three years of age and older; 2) Fluzone High Dose Quadrivalent (IIV4-HD) may be considered an option for individuals 65 years of age and older who are currently recommended to receive Fluzone High Dose (trivalent); and 3) Flucelvax Quad may be considered amongst the quadrivalent influenza vaccines offered to adults and children nine years of age and older for annual influenza immunization. Guidance for use of influenza immunizations during the coronavirus disease 2019 pandemic is also highlighted.

CONCLUSION

NACI continues to recommend that an age-appropriate influenza vaccine should be offered annually to anyone six months of age and older who does not have contraindications to the vaccine. Vaccination should be offered as a priority to people at high risk of influenza-related complications or hospitalization, people capable of transmitting influenza to those at high risk of complications, and others as indicated.

摘要

背景

加拿大已批准多种流感疫苗,且流感免疫的证据也在不断演变。国家免疫咨询委员会(NACI)每年都会就季节性流感疫苗的使用向加拿大公共卫生署(PHAC)提供建议。

目的

总结NACI关于2021 - 2022年季节性流感疫苗使用的建议,并突出新建议。

方法

NACI流感工作组制定年度流感疫苗建议,以供NACI审议和批准。这些建议的制定基于NACI循证流程。

结果

提出了以下新建议:1)对于向3岁及以上成人和儿童提供的标准剂量四价灭活流感疫苗(IIV4 - SD),可考虑将流感四价疫苗(Influvac Tetra)作为一种选择;2)对于目前建议接种高剂量流感疫苗(三价)的65岁及以上人群,可考虑将四价高剂量流感疫苗(Fluzone High Dose Quadrivalent,IIV4 - HD)作为一种选择;3)对于向9岁及以上成人和儿童提供的用于年度流感免疫的四价流感疫苗中,可考虑将四价流感病毒裂解疫苗(Flucelvax Quad)。还强调了2019冠状病毒病大流行期间流感免疫接种使用的指导意见。

结论

NACI继续建议,每年应向任何6个月及以上且无疫苗接种禁忌证的人提供适合其年龄的流感疫苗。应优先为有流感相关并发症或住院高风险的人群、能够将流感传播给有并发症高风险人群的人以及其他有指征的人群接种疫苗。