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桂甲散神阙穴贴敷在治疗肥胖型多囊卵巢综合征中可提高肥胖、内分泌及中医症状评分。

Application of Guijiaosan Shenque acupoint paste can improve the scores of obesity, endocrine and TCM symptoms in treating obese polycystic ovary syndrome.

作者信息

Shao Chao, Dong Wei, Zhang Hong

机构信息

Department of Gynaecology, South District of Guang'anmen Hospital Beijing 102600, China.

Department of Gynaecology, Guang'anmen Hospital Beijing 100053, China.

出版信息

Am J Transl Res. 2021 Sep 15;13(9):10694-10702. eCollection 2021.

Abstract

OBJECTIVE

To explore the effect of Guijiaosan Shenque acupoint paste on the obesity, endocrine, and TCM symptom scores of obese polycystic ovary syndrome (PCOS) patients with phlegm-dampness block.

METHODS

From January 2020 to December 2020, 80 PCOS patients with phlegm-dampness block were recruited as the study cohort and randomly divided into a research group (RG) or a control group (CG), with 40 cases in each group. The CG was treated with herbal decoctions according to syndrome differentiation, while the RG was administered Guijiaosan paste at the Shenque acupoint in addition to the treatment administered to the CG. The body weight indexes, endocrine function, insulin resistance indexes, TCM syndrome scores, and safety index changes were compared between the two groups before and after the treatment.

RESULTS

Compared with the CG, the body weight indexes, endocrine function, insulin resistance indexes, and TCM syndrome scores in the RG were significantly improved (P<0.05), and there was no significant difference in the safety indexes between the two groups before the treatment (P>0.05).

CONCLUSION

The application of Guijiaosan paste at the Shenque acupoint can effectively improve the obesity and endocrine functions of obese patients with PCOS and improve their clinical symptoms, so it is worthy of clinical promotion.

摘要

目的

探讨桂甲散神阙穴贴敷对痰湿阻滞型肥胖多囊卵巢综合征(PCOS)患者肥胖、内分泌及中医症状评分的影响。

方法

选取2020年1月至2020年12月收治的80例痰湿阻滞型PCOS患者作为研究队列,随机分为研究组(RG)和对照组(CG),每组40例。对照组根据辨证采用中药汤剂治疗,研究组在对照组治疗基础上加用桂甲散贴敷神阙穴。比较两组治疗前后体重指数、内分泌功能、胰岛素抵抗指数、中医证候评分及安全性指标变化。

结果

与对照组相比,研究组体重指数、内分泌功能、胰岛素抵抗指数及中医证候评分均显著改善(P<0.05),两组治疗前安全性指标比较差异无统计学意义(P>0.05)。

结论

神阙穴贴敷桂甲散可有效改善肥胖PCOS患者的肥胖及内分泌功能,改善其临床症状,值得临床推广。

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本文引用的文献

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Lifestyle changes in women with polycystic ovary syndrome.多囊卵巢综合征女性的生活方式改变
Cochrane Database Syst Rev. 2019 Mar 28;3(3):CD007506. doi: 10.1002/14651858.CD007506.pub4.
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Polycystic ovary syndrome in adult women.成年女性多囊卵巢综合征。
Med Clin (Barc). 2019 Jun 7;152(11):450-457. doi: 10.1016/j.medcli.2018.11.019. Epub 2019 Jan 4.

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