de Borges R J, Acevedo F, Miralles E, Mijares P
Acta Cytol. 1986 Sep-Oct;30(5):487-90.
Esophageal material for cytologic smears was obtained by the gel-foam technique from an 84-year-old man with dysphagia and symptoms of obstruction in whom initial attempts at endoscopic biopsy were nondiagnostic. The smears contained cells with koilocytotic atypia, similar to those described in smears from uterine cervix lesions produced by human papilloma virus. The cytologic diagnosis of an esophageal papilloma of viral origin was confirmed by the second biopsy. A third biopsy, from a lower level of the esophagus following dilatation procedures, revealed an epidermoid carcinoma in situ contiguous with the papilloma.
通过凝胶泡沫技术从一名84岁吞咽困难且有梗阻症状的男性获取食管细胞学涂片材料，该患者最初的内镜活检未能明确诊断。涂片中有核周空泡化非典型细胞，类似于人乳头瘤病毒引起的子宫颈病变涂片中所描述的细胞。第二次活检证实了病毒源性食管乳头状瘤的细胞学诊断。在扩张手术后，从食管较低部位进行的第三次活检显示，与乳头状瘤相邻处有原位表皮样癌。
