68Ga-FAPI PET/CT 可区分鼻咽癌患者反应性淋巴结与肿瘤转移淋巴结。
68Ga-FAPI PET/CT Distinguishes the Reactive Lymph Nodes From Tumor Metastatic Lymph Nodes in a Patient With Nasopharyngeal Carcinoma.
机构信息
From the Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Center, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Department of Radiation Oncology, Xiamen Cancer Center, The First Affiliated Hospital of Xiamen University, Xiamen, China.
出版信息
Clin Nucl Med. 2022 Apr 1;47(4):367-368. doi: 10.1097/RLU.0000000000003939.
Accurate clinical staging is crucial for managing nasopharyngeal carcinoma (NPC). However, false-positive finding of cervical lymph nodes in 18F-FDG PET/CT and MRI may lead to unnecessary chemotherapy for NPC. In this case, we report a patient with NPC who was incorrectly diagnosed with bilateral cervical lymph node metastases by both 18F-FDG PET/CT and MRI. Subsequent pathology results showed proliferating lymphoid cells with no signs of tumor metastasis. Interestingly, no abnormal 68Ga-FAPI uptake was observed in the nonmetastatic reactive lymph nodes. Therefore, 68Ga-FAPI PET/CT may be useful for assessment of pretreatment lymph node status in NPC.
准确的临床分期对于管理鼻咽癌（NPC）至关重要。然而，18F-FDG PET/CT 和 MRI 对颈部淋巴结的假阳性发现可能导致 NPC 的不必要化疗。在这种情况下，我们报告了一例 NPC 患者，该患者被 18F-FDG PET/CT 和 MRI 均误诊为双侧颈部淋巴结转移。随后的病理结果显示增生的淋巴细胞，没有肿瘤转移的迹象。有趣的是，非转移性反应性淋巴结中没有观察到异常的 68Ga-FAPI 摄取。因此，68Ga-FAPI PET/CT 可能有助于评估 NPC 患者的治疗前淋巴结状态。
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