Department of Neuroses, Personality Disorders, and Eating Disorders, Institute of Psychiatry and Neurology, Warsaw, Poland.
II Department of Psychiatry, Medical University of Warsaw, Warsaw, Poland.
Eur Eat Disord Rev. 2021 Nov;29(6):879-892. doi: 10.1002/erv.2862. Epub 2021 Oct 15.
The possible role of abnormal disgust processing in the development and course of anorexia nervosa (AN) has been emphasized in theoretical models and research. However, disgust toward external stimuli and self-disgust have not yet been investigated together in a clinical sample of AN patients. Therefore, the purpose of the study was to measure these constructs and examine their role in shaping eating pathology in AN patients and healthy controls (HCs), considering comorbid depressive and anxiety psychopathology. The study also aimed at testing the possible mediational roles of both disgust types in the associations between comorbid psychopathology and eating disorders (EDs) characteristics.
Altogether, 63 inpatients with AN and 57 HCs partook in the study. Participants completed the Eating Disorder Inventory-3, State-Trait Anxiety Inventory, Beck Depression Inventory-II, Disgust Scale-Revised and Self-Disgust Scale.
AN patients manifested higher self-disgust and disgust sensitivity than HCs. In addition, self-disgust predicted the severity of EDs characteristics and mediated the links of depressive symptoms and trait anxiety with EDs characteristics in both groups.
Our findings imply the putative role of self-disgust in the development of EDs psychopathology in HCs and in its maintenance in AN patients.
在理论模型和研究中强调了异常厌恶处理在厌食症（AN）的发展和病程中的可能作用。然而，在 AN 患者的临床样本中，尚未同时研究对外界刺激的厌恶和自我厌恶。因此，本研究的目的是测量这些结构，并考虑共病抑郁和焦虑性精神病理学，研究它们在塑造 AN 患者和健康对照组（HCs）的进食病理方面的作用。该研究还旨在检验这两种厌恶类型在共病精神病理学和饮食障碍（EDs）特征之间的关联中的可能中介作用。
共有 63 名 AN 住院患者和 57 名 HCs 参加了这项研究。参与者完成了饮食障碍问卷-3、状态-特质焦虑量表、贝克抑郁量表-2、修订版厌恶量表和自我厌恶量表。
AN 患者表现出自我厌恶和厌恶敏感性高于 HCs。此外，自我厌恶预测了 EDs 特征的严重程度，并在两组中中介了抑郁症状和特质焦虑与 EDs 特征之间的联系。
我们的发现表明，自我厌恶在 HCs 中 EDs 精神病理学的发展及其在 AN 患者中的维持中具有潜在作用。
