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定义腰椎手术的相对效用:常见手术程序及其对健康状况影响的系统文献回顾。

Defining the relative utility of lumbar spine surgery: A systematic literature review of common surgical procedures and their impact on health states.

机构信息

Department of Neurological Surgery, Wellstar Health System, Austell, GA, United States.

Vanderbilt University School of Medicine, Nashville, TN, United States.

出版信息

J Clin Neurosci. 2021 Nov;93:160-167. doi: 10.1016/j.jocn.2021.09.003. Epub 2021 Sep 20.

DOI:10.1016/j.jocn.2021.09.003
PMID:34656241
Abstract

Degenerative lumbar spondylosis is a common indication for patients undergoing spine surgery. As healthcare costs rise, measuring quality of life (QOL) gains after surgical procedures is critical in assessing value. We set out to: 1) compare baseline and postoperative EuroQol-5D (EQ-5D) scores for lumbar spine surgery and common surgical procedures to obtain post-operative quality-adjusted life year (QALY) gain, and 2) establish the relative utility of lumbar spine surgery as compared to other commonly performed surgical procedures. A systematic literature review was conducted to identify all studies reporting preoperative/baseline and postoperative EQ-5D scores for common surgical procedures. For each study, the number of patients included and baseline/preoperative and follow-up mean EQ-5D scores were recorded, and mean QALY gained for each intervention was calculated. A total of 67 studies comprising 95,014 patients were identified. Patients with lumbar spondylosis had the worst reported QOL at baseline compared to other surgical cohorts. The greatest QALY gain was seen in patients undergoing hip arthroplasty (0.38), knee arthroplasty (0.35) and lumbar spine surgery (0.32), nearly 2.5-fold greater QALY gained than for all other procedures. The low preoperative QOL, coupled with the improvements offered with surgery, highlight the utility and value of lumbar spine surgery compared to other common surgical procedures.

摘要

退行性腰椎疾病是脊柱手术患者的常见指征。随着医疗保健成本的上升,衡量手术治疗后的生活质量(QOL)增益对于评估价值至关重要。我们旨在:1)比较腰椎手术和常见手术的基线和术后欧洲五维健康量表(EQ-5D)评分,以获得术后质量调整生命年(QALY)增益,2)确定与其他常见手术相比,腰椎手术的相对效用。进行了系统的文献综述,以确定所有报告常见手术术前/基线和术后 EQ-5D 评分的研究。对于每项研究,记录了纳入的患者数量以及基线/术前和随访的平均 EQ-5D 评分,并计算了每项干预措施的平均 QALY 增益。共确定了 67 项研究,涉及 95014 名患者。与其他手术队列相比,腰椎疾病患者的基线报告 QOL 最差。髋关节置换术(0.38)、膝关节置换术(0.35)和腰椎手术(0.32)患者的 QALY 增益最大,几乎是所有其他手术的 2.5 倍。术前 QOL 较低,加上手术带来的改善,突显了与其他常见手术相比,腰椎手术的效用和价值。

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