脑膜淋巴管：β-淀粉样蛋白免疫疗法的调节者？
The meningeal lymphatics: regulators of Aβ immunotherapy?
机构信息
Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA.
Department of Pathology and Laboratory Medicine, University of Wisconsin Madison, School of Medicine and Public Health, 1111 Highland Avenue, Madison, WI 53705, USA.
出版信息
Trends Immunol. 2021 Nov;42(11):940-942. doi: 10.1016/j.it.2021.09.011. Epub 2021 Oct 13.
A new study by Da Mesquita et al. reports on how meningeal lymphatic modulation may influence amyloid-beta immunotherapy and microglial function in mouse models of Alzheimer's disease (AD). This research has broad implications for unraveling the role meningeal lymphatics may play in regulating immunity in the brain during AD pathology and treatment.
一项由 Da Mesquita 等人开展的新研究报告了脑膜淋巴管调节如何影响阿尔茨海默病（AD）小鼠模型中的淀粉样蛋白-β免疫疗法和小胶质细胞功能。这项研究对于揭示脑膜淋巴管在 AD 病理和治疗过程中调节大脑免疫方面的作用具有广泛意义。
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