Suppr超能文献

统计学意义还是临床意义?研究人员在正确解读研究结果方面的困境。

Statistical significance or clinical significance? A researcher's dilemma for appropriate interpretation of research results.

作者信息

Sharma Hunny

机构信息

Department of Community and Family Medicine, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.

出版信息

Saudi J Anaesth. 2021 Oct-Dec;15(4):431-434. doi: 10.4103/sja.sja_158_21. Epub 2021 Sep 2.

Abstract

It is incredibly essential that the current clinicians and researchers remain updated with findings of current biomedical literature for evidence-based medicine. However, they come across many types of research that are nonreproducible and are even difficult to interpret clinically. Statistical and clinical significance is one such difficulty that clinicians and researchers face across many instances. In simpler terms, the value tests all hypothesis about how the data were produced (model as whole), and not just the targeted hypothesis that it is intended to test (such as a null hypothesis) keeping in mind how reliable are the of the research results. Most of the times it is misinterpreted and misunderstood as a measure to judge the results as clinically significant. Hence this review aims to impart knowledge about "P" value and its importance in biostatistics, also highlights the importance of difference between statistical and clinical significance for appropriate interpretation of research results.

摘要

对于当前的临床医生和研究人员而言,紧跟当前生物医学文献的研究结果以实现循证医学是极其重要的。然而,他们会遇到许多无法重复且临床解释起来甚至都很困难的研究类型。统计显著性和临床显著性就是临床医生和研究人员在很多情况下都会面临的一个难题。简单来说,P值检验的是关于数据如何产生的所有假设(整体模型),而不仅仅是它打算检验的目标假设(例如零假设),同时要牢记研究结果的可靠性如何。大多数时候,它被误解和错误地当作判断结果是否具有临床显著性的一种度量。因此,本综述旨在传授关于“P”值及其在生物统计学中的重要性的知识,同时也强调统计显著性和临床显著性之间的差异对于正确解释研究结果的重要性。

相似文献

2
Understanding statistical significance.理解统计显著性。
Nurs Res. 2010 May-Jun;59(3):219-23. doi: 10.1097/NNR.0b013e3181dbb2cc.
4
The future of Cochrane Neonatal.考克兰新生儿协作网的未来。
Early Hum Dev. 2020 Nov;150:105191. doi: 10.1016/j.earlhumdev.2020.105191. Epub 2020 Sep 12.
8
Statistics in ophthalmology revisited: the (effect) size matters.眼科统计学再探:(效应)大小很重要。
Acta Ophthalmol. 2018 Nov;96(7):e885-e888. doi: 10.1111/aos.13756. Epub 2018 Sep 5.

引用本文的文献

5
Effect of general anesthesia on postoperative pulmonary embolism.全身麻醉对术后肺栓塞的影响。
Ann Med. 2025 Dec;57(1):2530228. doi: 10.1080/07853890.2025.2530228. Epub 2025 Jul 10.

本文引用的文献

2
What the values really tell us.这些数值真正告诉我们的是什么。
Korean J Pain. 2017 Oct;30(4):241-242. doi: 10.3344/kjp.2017.30.4.241. Epub 2017 Sep 29.
3
P value interpretations and considerations.P值的解读与考量。
J Thorac Dis. 2016 Sep;8(9):E928-E931. doi: 10.21037/jtd.2016.08.16.
7
Error of the method: what is it for?该方法的误差:其用途是什么?
Dental Press J Orthod. 2014 Mar-Apr;19(2):25-6. doi: 10.1590/2176-9451.19.2.025-026.ebo.
9
Using Effect Size-or Why the P Value Is Not Enough.使用效应量——为何P值并不足够。
J Grad Med Educ. 2012 Sep;4(3):279-82. doi: 10.4300/JGME-D-12-00156.1.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验