Yang Juan-Juan, Cai Hong, Xia Lei, Nie Weicheng, Zhang Yulong, Wang Song, Shi Yudong, Ng Chee H, Liu Huanzhong, Xiang Yu-Tao
Department of Psychiatry, School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, China.
Department of Psychiatry, Chaohu Hospital of Anhui Medical University, Hefei, China.
Front Psychiatry. 2021 Sep 22;12:727939. doi: 10.3389/fpsyt.2021.727939. eCollection 2021.
There are few studies on the epidemiology of depression, insomnia, and their association with quality of life (QOL) in older adults living in rural China. This study examined the prevalence of depressive and insomnia symptoms, and their association with QOL in community-dwelling older adults in a rural area in Anhui province, China. This was a cross-sectional study conducted in the rural areas of four cities (Hefei, Huaibei, Anqing, and Xuancheng) in Anhui province between July and October, 2019 using random sampling method. All community-dwelling residents from the selected villages who met the study entry criteria were invited to participate in this study. Depressive and insomnia symptoms and QOL were assessed with the Chinese version of self-reported Center for Epidemiological Survey Depression Scale (CES-D), the Insomnia Severity Index (ISI) and the 26-item World Health Organization Quality of Life Brief version (WHOQOL-BREF), respectively. A total of 871 older adults were included. The prevalence of overall depressive symptoms, insomnia symptoms, and comorbid depressive and insomnia symptoms were 34.0% [95% confidence intervals (95% CI): 30.8-37.1%], 45.7% (95% CI: 42.4-49.0%) and 20.3% (95% CI: 17.6-23.0%), respectively. Older adults with depressive symptoms, insomnia symptoms, and comorbid depressive and insomnia symptoms had lower scores in QOL compared to those without. Depressive symptoms were positively associated with living with families [Odd Ratio (OR) = 1.82, 95% CI: 1.31-2.54] and negatively associated with current drinking (OR = 0.49, 95% CI: 0.33-0.72). Insomnia symptoms were negatively associated with fair and good financial status (fair: OR = 0.53, 95% CI = 0.38-0.75; good: OR = 0.30, 95% CI = 0.14-0.64) and current drinking (OR = 0.64, 95% CI = 0.45-0.93), and positively associated with more frequent major medical conditions (OR = 1.32, 95% CI = 1.16-1.51). Comorbid depressive and insomnia symptoms were positively associated with living with families (OR = 2.02, 95% CI = 1.36-3.00), and negatively associated with fair and good financial status (fair: OR = 0.61, 95% CI = 0.41-0.89; good: OR = 0.34, 95% CI = 0.12-0.95) and current drinking (OR = 0.57, 95% CI = 0.35-0.92). Depressive and insomnia symptoms were common in older adults living in rural areas in China. Considering the negative health outcomes caused by depressive and insomnia symptoms, regular screening and effective treatments should be developed for this population.
关于中国农村老年人抑郁症、失眠症的流行病学及其与生活质量(QOL)的关联的研究较少。本研究调查了中国安徽省某农村地区社区居住老年人抑郁症状和失眠症状的患病率及其与生活质量的关联。这是一项横断面研究,于2019年7月至10月在安徽省四个城市(合肥、淮北、安庆和宣城)的农村地区采用随机抽样方法进行。所有来自选定村庄且符合研究纳入标准的社区居住居民均被邀请参与本研究。抑郁症状、失眠症状和生活质量分别采用中文版自填式流行病学研究中心抑郁量表(CES-D)、失眠严重程度指数(ISI)和26项世界卫生组织生活质量简表(WHOQOL-BREF)进行评估。共纳入871名老年人。总体抑郁症状、失眠症状以及抑郁与失眠共病症状的患病率分别为34.0%[95%置信区间(95%CI):30.8 - 37.1%]、45.7%(95%CI:42.4 - 49.0%)和20.3%(95%CI:17.6 - 23.0%)。与无抑郁症状、失眠症状以及抑郁与失眠共病症状的老年人相比,有这些症状的老年人生活质量得分更低。抑郁症状与与家人同住呈正相关[比值比(OR)=1.82,95%CI:1.31 - 2.54],与当前饮酒呈负相关(OR = 0.49,95%CI:0.33 - 0.72)。失眠症状与经济状况一般和良好呈负相关(一般:OR = 0.53,95%CI = 0.38 - 0.75;良好:OR = 0.30,95%CI = 0.14 - 0.64)以及与当前饮酒呈负相关(OR = 0.64,95%CI = 0.45 - 0.93),与更频繁的重大疾病呈正相关(OR = 1.32,95%CI = 1.16 - 1.51)。抑郁与失眠共病症状与与家人同住呈正相关(OR = 2.02,95%CI = 1.36 - 3.00),与经济状况一般和良好呈负相关(一般:OR = 0.61,95%CI = 0.41 - 0.89;良好:OR = 0.34,95%CI = 0.12 - 0.95)以及与当前饮酒呈负相关(OR = 0.57,95%CI = 0.35 - 0.92)。抑郁症状和失眠症状在中国农村老年人中很常见。考虑到抑郁症状和失眠症状所导致的负面健康后果,应为该人群开展定期筛查和有效治疗。