Chen Y, Sun G, Guo X, Chen S, Chang Y, Li Y, Sun Y
First Hospital of China Medical University, Shenyang, China.
First Hospital of China Medical University, Shenyang, China.
Public Health. 2017 May;146:140-147. doi: 10.1016/j.puhe.2017.01.023. Epub 2017 Feb 27.
The brief version of the World Health Organization's Quality of Life Instrument (WHOQOL-BREF) is widely used for evaluating the personal subjective quality of life (QOL) of patients and particular populations. However, in the absence of sufficient studies among the general population, normative data for WHOQOL-BREF remain scarce. To fill this gap, the present study explored more sociodemographic and health-related factors affecting the QOL.
In total, 11,351 participants aged ≥35 years in rural areas of Liaoning Province were screened with a stratified cluster multistage sampling scheme in 2012-2013. Anthropometric measurements, laboratory examinations, and self-reported information on disease history were collected by trained personnel. Depression symptoms were assessed using the Patient Health Questionnaire-9.
Stepwise multiple linear regression was used to explore the association between multiple factors and QOL.
Females and single/widowed subjects had lower QOL scores than males and married/cohabiting subjects, respectively. Total QOL scores and scores for each domain decreased as age increased, but a positive correlation was found between age and the environmental domain score. Participants with higher annual incomes, education levels, and activity levels had higher QOL scores. In the regression model, the coefficient for stroke was -2.17 (95% confidence interval [CI] -2.64, -1.71) for the total QOL score. For a one-level increase in depression level, the total QOL score decreased by 5.62 (95% CI -5.83 to -5.42), physical domain score decreased by 1.63 (95% CI -1.69 to -1.58), and psychological domain score decreased by 1.81 (95% CI -1.87 to -1.75).
Socio-economic status including marital status is highly related to QOL. Regarding chronic diseases, stroke is an important factor of QOL and depressive symptoms have a strong negative relationship with QOL.
世界卫生组织生活质量量表简表（WHOQOL - BREF）被广泛用于评估患者及特定人群的个人主观生活质量（QOL）。然而，由于普通人群中相关研究不足，WHOQOL - BREF的常模数据仍然匮乏。为填补这一空白，本研究探讨了更多影响生活质量的社会人口学和健康相关因素。
2012 - 2013年，采用分层整群多阶段抽样方案，对辽宁省农村地区11351名年龄≥35岁的参与者进行了筛查。由经过培训的人员收集人体测量数据、实验室检查结果以及关于疾病史的自我报告信息。使用患者健康问卷 - 9评估抑郁症状。
采用逐步多元线性回归探讨多个因素与生活质量之间的关联。
女性和单身/丧偶者的生活质量得分分别低于男性和已婚/同居者。总体生活质量得分及各领域得分均随年龄增长而降低，但年龄与环境领域得分呈正相关。年收入、教育水平和活动水平较高的参与者生活质量得分较高。在回归模型中，中风因素对总体生活质量得分的系数为 - 2.17（95%置信区间[CI] - 2.64， - 1.71）。抑郁水平每升高一级，总体生活质量得分降低5.62（95% CI - 5.83至 - 5.42），生理领域得分降低1.63（95% CI - 1.69至 - 1.58），心理领域得分降低1.81（95% CI - 1.87至 - 1.75）。
包括婚姻状况在内的社会经济状况与生活质量高度相关。对于慢性病，中风是影响生活质量的重要因素，抑郁症状与生活质量呈强烈负相关。
