急性播散性脑脊髓炎：新冠病毒嗜神经性的一种罕见形式。
Acute Disseminated Encephalomyelitis: A rare form of COVID-19's neurotropism.
作者信息
Berrichi Samia, Bouayed Zakaria, Berrajaa Sara, Bahouh Choukri, Oulalite Amine Mohammed, Douqchi Badie, Bella Islam, Bkiyar Houssam, Housni Brahim
机构信息
Department of Anesthesiology, Intensive Care Medicine and Resuscitation, MOHAMMED VI University Hospital Center, Oujda, Morocco.
Simulation Center, Faculty of Medicine and Pharmacy, Oujda, Morocco.
出版信息
Ann Med Surg (Lond). 2021 Nov;71:102940. doi: 10.1016/j.amsu.2021.102940. Epub 2021 Oct 11.
INTRODUCTION
the COVID-19 pandemic still accounts for thousands of cases every day. It's neurological involvement has been well documented most likely due to auto-immune mechanisms than the virus itself.
CASE REPORT
we report the case of a 38 years old women who developed an Acute Disseminated Encephalomyelitis following a COVID-19 infection, with a favorable outcome after immunosuppressive therapy.
DISCUSSION
In this chapter, we discuss ADEM's pathogenesis as well as its clinical and radiological features before detailing its relationship with infectious and vaccination episodes. We also discuss how our patient disease evolved.
CONCLUSION
Acute Disseminated Encephalomyelitis is an immune-mediated disorder in which the widespread inflammation of the brain and spinal cord is responsible for a variety of symptoms. The novel COVID-19 virus and its vaccine are both a newly incriminated etiologies of this demyelinating disorder.
引言
新冠疫情至今每天仍有数千病例。其神经系统受累情况已有充分记录，这很可能是由自身免疫机制而非病毒本身导致的。
病例报告
我们报告一例38岁女性病例，该患者在感染新冠病毒后患上急性播散性脑脊髓炎，经免疫抑制治疗后预后良好。
讨论
在本章中，我们先讨论急性播散性脑脊髓炎的发病机制及其临床和放射学特征，再详细阐述其与感染及疫苗接种事件的关系。我们还讨论了我们这位患者的病情是如何发展的。
结论
急性播散性脑脊髓炎是一种免疫介导的疾病，大脑和脊髓的广泛炎症会引发各种症状。新型新冠病毒及其疫苗都是这种脱髓鞘疾病新发现的病因。
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