The Hospital of Central Connecticut, Hartford Healthcare, 100 Grand St., New Britain, CT, 06052, USA.
University of Connecticut School of Medicine, Farmington, CT, USA.
J Neurol. 2020 Oct;267(10):2799-2802. doi: 10.1007/s00415-020-09951-9. Epub 2020 May 30.
A 51-year-old woman with COVID-19 infection developed coma and an impaired oculocephalic response to one side. MRI of the brain demonstrated acute multifocal demyelinating lesions, and CSF testing did not identify a direct cerebral infection. High-dose steroids followed by a course of IVIG was administered, and the patient regained consciousness over the course of several weeks. As more patients reach the weeks after initial infection with COVID-19, acute disseminated encephalomyelitis should be considered a potentially treatable cause of profound encephalopathy or multifocal neurological deficits.
一位 51 岁的 COVID-19 感染女性患者出现昏迷和单侧眼球运动反应障碍。脑部 MRI 显示急性多灶性脱髓鞘病变，CSF 检测未发现直接脑部感染。给予大剂量类固醇和静脉注射免疫球蛋白治疗后，患者在数周内恢复意识。随着越来越多的患者在 COVID-19 初始感染后数周，急性播散性脑脊髓炎应被视为一种潜在可治疗的严重脑病或多灶性神经功能缺损的原因。
