Gogia Bhanu, Thottempudi Neeharika, Ajam Yousaf, Singh Ayush, Ghanayem Tamer, Dabi Alok, Fang Xiang, Masel Todd, Rai Prashant
Vascular Neurology/Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA.
Neurology, University of Texas Medical Branch at Galveston, Galveston, USA.
Cureus. 2021 Oct 4;13(10):e18476. doi: 10.7759/cureus.18476. eCollection 2021 Oct.
The objective of this study is to report EEG findings in both COVID-19 survivors and non-survivors who underwent EEG either due to seizure or encephalopathy. Out of total 1468 COVID-19-positive patients, 19 patients underwent EEG. Eight out of 19 patients had a history of seizure disorder and in the remaining 11 with no prior history of seizures, four had a clinical seizure during their hospital stay. Only one had new-onset complex focal status epilepticus on EEG. Amongst the survivors (13/19), the most common EEG findings were normal followed by mild diffuse slowing. Amongst the non-survivors (6/19), the most common EEG finding was moderate to severe slowing in 50% of the patients. It can be deduced that COVID-19 infection does not increase the propensity of epileptiform discharges on EEG. There is perhaps a trend towards increased risk of new-onset status epilepticus in patients with encephalopathy and focal lesions.
本研究的目的是报告因癫痫发作或脑病接受脑电图（EEG）检查的新冠病毒疾病（COVID-19）幸存者和非幸存者的EEG结果。在总共1468例COVID-19阳性患者中，19例接受了EEG检查。19例患者中有8例有癫痫病史，其余11例无癫痫病史，其中4例在住院期间出现临床癫痫发作。EEG检查仅1例出现新发复杂性局灶性癫痫持续状态。在幸存者（13/19）中，最常见的EEG结果是正常，其次是轻度弥漫性减慢。在非幸存者（6/19）中，最常见的EEG结果是50%的患者出现中度至重度减慢。可以推断，COVID-19感染不会增加EEG上癫痫样放电的倾向。脑病和局灶性病变患者新发癫痫持续状态的风险可能有增加趋势。
