Dharmasena F, Littlewood T, Gordon-Smith E C, Catovsky D, Galton D A
Clin Lab Haematol. 1986;8(4):361-4. doi: 10.1111/j.1365-2257.1986.tb00124.x.
We report two adult patients who presented with bone marrow aplasia and latterly were diagnosed to have acute lymphoblastic leukaemia (ALL). Although the aplastic presentation of ALL in childhood is well documented it has not been previously reported in adult ALL. The mechanism of this presentation is unclear. In one of our patients folate deficiency appears to have been the cause.
我们报告了两名成年患者，他们最初表现为骨髓再生障碍，后来被诊断为急性淋巴细胞白血病（ALL）。尽管儿童ALL的再生障碍表现已有充分记录，但此前在成人ALL中尚未有过报道。这种表现的机制尚不清楚。在我们的一名患者中，叶酸缺乏似乎是病因。
