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腹腔镜引导下 TAPP 腹股沟疝修补术中的局部区域麻醉浸润技术:一项双盲随机临床试验。

Laparoscopic-guided distal loco-regional anesthetic infiltration technique in TAPP inguinal hernia repair: a double-blind randomized clinical trial.

机构信息

General Surgery Department, Hospital Italiano de Buenos Aires, Tte. Gral Juan Domingo Perón 4190, Ciudad Autónoma de Buenos Aires, Argentina.

Microsurgery and Abdominal Wall Reconstruction Section, General Surgery Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

出版信息

Surg Endosc. 2022 Jun;36(6):4312-4320. doi: 10.1007/s00464-021-08775-6. Epub 2021 Oct 19.

Abstract

BACKGROUND

Ultrasound-guided transversus abdominis plane block (US-TAP) is an important component of multimodal analgesia in laparoscopic inguinal hernia repair, although it has certain limitations. To overcome them, surgeons have developed several techniques to perform local anesthetic infiltration under laparoscopic guidance, but no trials evaluating these in transabdominal preperitoneal (TAPP) hernia repair were conducted till the date. The aim of this study was to compare the efficacy of a novel laparoscopic-guided local anesthetic infiltration technique (LDAI) with US-TAP in postoperative pain control and analgesic consumption for patients undergoing elective TAPP hernia repair.

METHODS

This was a double-blind randomized controlled trial conducted at a single tertiary academic center between 2019 and 2020 on adult patients undergoing elective laparoscopic TAPP inguinal hernia repair. Postoperative pain and analgesic consumption were compared for LDAI vs. US-TAP up to 30 postoperative days.

RESULTS

62 patients were included (31 LDAI, 31 US-TAP). Female gender was significantly higher in the LDAI group (8, 25.81%; US-TAP 0; p = 0.005). Mean anesthetic time (US-TAP group: 142.2 min, SD = 17.7; LDAI group: 127.1 min, SD = 15.5; p < 0.001) and mean operative time (US-TAP group: 117.2 min, SD = 15.9; LDAI group: 103.8 min, SD = 15.2; p < 0.001) were significantly shorter in the LDAI group. Pain scores assessed at the first-hour postoperative, at the moment of discharge, and at 8, 24, and 48 postoperative hours showed no significant differences between both groups. No significant difference was found regarding postoperative analgesic rescue administration in the recovery room and analgesic consumption after discharge between groups.

CONCLUSION

LDAI is a safe and effective local anesthetic technique in elective TAPP hernia repair. Pain control is similar to US-TAP block, with shorter anesthesthetic and surgical time and better health resources allocation.

摘要

背景

超声引导腹横肌平面阻滞(US-TAP)是腹腔镜腹股沟疝修补术多模式镇痛的重要组成部分,但存在一定局限性。为了克服这些局限性,外科医生已经开发了几种在腹腔镜引导下进行局部麻醉浸润的技术,但直到目前为止,还没有评估这些技术在经腹腹膜前(TAPP)疝修补术中的临床试验。本研究的目的是比较新型腹腔镜引导下局部麻醉浸润技术(LDAI)与 US-TAP 在接受择期 TAPP 疝修补术的患者中的术后疼痛控制和镇痛消耗的效果。

方法

这是一项在 2019 年至 2020 年期间在一家单中心三级学术中心进行的双盲随机对照试验,纳入了接受择期腹腔镜 TAPP 腹股沟疝修补术的成年患者。比较了 LDAI 与 US-TAP 组在术后 30 天内的术后疼痛和镇痛消耗。

结果

共纳入 62 例患者(LDAI 组 31 例,US-TAP 组 31 例)。LDAI 组女性明显多于 US-TAP 组(8 例,25.81%;US-TAP 组 0 例;p=0.005)。麻醉时间(US-TAP 组:142.2 分钟,SD=17.7;LDAI 组:127.1 分钟,SD=15.5;p<0.001)和手术时间(US-TAP 组:117.2 分钟,SD=15.9;LDAI 组:103.8 分钟,SD=15.2;p<0.001)均显著短于 LDAI 组。术后第 1 小时、出院时、术后 8、24 和 48 小时的疼痛评分在两组间无显著差异。两组患者在恢复室的术后镇痛解救药物的使用和出院后的镇痛消耗方面均无显著差异。

结论

LDAI 是一种安全有效的择期 TAPP 疝修补术局部麻醉技术。疼痛控制与 US-TAP 阻滞相似,麻醉和手术时间更短,可更好地分配卫生资源。

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