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腹横肌平面(TAP)阻滞能否改善腹腔镜双侧腹股沟疝修补术后恢复病房之外的疼痛?一项随机对照试验。

Do transversus abdominis plane (TAP) blocks improve pain after laparoscopic bilateral inguinal hernia repairs beyond the recovery unit? A randomized control trial.

作者信息

Agathis Alexandra Z, Mathney Edward R, Higgins Madeleine S, Tufts Lauren S, Wu Jeanne Z, Sherwin Marc, Zhang Linda P, Divino Celia M

机构信息

Department of Surgery, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1259, New York, NY, 10029, USA.

Department of Anesthesia, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

出版信息

Hernia. 2025 Jan 11;29(1):66. doi: 10.1007/s10029-025-03261-7.

Abstract

PURPOSE

While surgeons agree that perioperative field blocks should be performed for open inguinal hernia surgery, there lacks consensus in the minimally invasive context. Prior small-scale randomized trials study pain scores only up to 24 h postoperatively. Thus, we sought to investigate the analgesic benefits of a bupivacaine transversus abdominis plane (TAP) block in the first 4 postoperative days.

METHODS

This is a prospective single-institution randomized control trial involving patients undergoing elective totally extraperitoneal inguinal hernia repairs, who received either a TAP block with bupivacaine 0.25% or saline placebo. Postoperatively, patients completed a pain survey (based on a 0-10 visual analog score) and an opioid/non-opioid pain medication log. Differences were detected using a Wilcoxon rank sum test for continuous variables, and a Fisher's exact test or chi-squared for categorical variables.

RESULTS

A total n = 90 patients were included in the per-protocol analysis, of which n = 46 received TAP blocks with bupivacaine versus n = 44 placebo. Patient characteristics were similar between the groups, including recurrent hernias and number of tacks placed (p > 0.05). All cases were bilateral. Postoperatively, pain scores (at rest and with movement) and pain medication use were similar for all postoperative days 1-4.

CONCLUSION

Our study shows no significant difference in pain or opioid requirement within the first 4 days postoperatively, suggesting that the analgesic benefits of plain bupivacaine TAP blocks in totally extraperitoneal inguinal hernia repairs do not exist beyond the recovery unit. This will help inform anesthesiologists and patients in discussing risks and benefits of a TAP block in their surgical context.

摘要

目的

虽然外科医生一致认为开放性腹股沟疝手术应进行围手术期区域阻滞,但在微创环境下尚未达成共识。先前的小规模随机试验仅研究术后24小时内的疼痛评分。因此,我们试图研究布比卡因腹横肌平面(TAP)阻滞在术后前4天的镇痛效果。

方法

这是一项前瞻性单机构随机对照试验,涉及接受择期完全腹膜外腹股沟疝修补术的患者,他们接受了0.25%布比卡因TAP阻滞或生理盐水安慰剂。术后,患者完成疼痛调查(基于0至10的视觉模拟评分)和阿片类/非阿片类疼痛药物使用记录。连续变量采用Wilcoxon秩和检验,分类变量采用Fisher精确检验或卡方检验来检测差异。

结果

符合方案分析共纳入n = 90例患者,其中n = 46例接受布比卡因TAP阻滞,n = 44例接受安慰剂。两组患者的特征相似,包括复发性疝和钉合数量(p > 0.05)。所有病例均为双侧。术后第1至4天,所有患者的疼痛评分(静息和活动时)及疼痛药物使用情况相似。

结论

我们的研究表明,术后前4天疼痛或阿片类药物需求无显著差异,这表明单纯布比卡因TAP阻滞在完全腹膜外腹股沟疝修补术中的镇痛效果在恢复室之外并不存在。这将有助于麻醉医生和患者在讨论手术中TAP阻滞的风险和益处时提供参考。

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