Suppr超能文献

腹腔镜辅助腹横肌平面阻滞在完全腹膜外腹股沟疝修补术中作为一种有效的镇痛方法:一项双盲、随机对照试验。

Laparoscopic-assisted transversus abdominis plane block as an effective analgesic in total extraperitoneal inguinal hernia repair: a double-blind, randomized controlled trial.

作者信息

Mughal A, Khan A, Rehman J, Naseem H, Waldron R, Duggan M, Khan W, Barry K, Khan I Z

机构信息

Department of Surgery, Mayo University Hospital, Saolta University Healthcare Group, Castlebar, Co Mayo, Ireland.

Department of Anaesthesia, Mayo University Hospital, Saolta University Healthcare Group, Castlebar, Co Mayo, Ireland.

出版信息

Hernia. 2018 Oct;22(5):821-826. doi: 10.1007/s10029-018-1819-8. Epub 2018 Sep 1.

Abstract

PURPOSE

Laparoscopic inguinal hernia repair has facilitated early mobilization. Management of post-operative pain is paramount in these day case procedures. The aim of this study was to compare laparoscopic-assisted transversus abdominis plane (TAP) block with periportal local anaesthetic infiltration in managing post-operative pain.

METHODS

A double-blind, randomized controlled trial was conducted with patients undergoing elective laparoscopic inguinal hernia repair (January 2016-October 2017). The intervention group received laparoscopic-assisted TAP block with 30 ml 0.25% Bupivacaine. The control group received 15ml of 0.5% Bupivacaine at the periportal sites. Primary outcome measure was assessment of post-operative pain scores using numerical rating on visual analogue scale (VAS) at rest and on coughing at 3 h. Efficacy of TAP block was assessed as reduction in mean pain scores in the order of 2 points using the VAS.

RESULTS

60 (57 males and 3 females) were enrolled; 30 patients were randomized to each group. Patient demographics, anaesthetic and surgical times were similar in both groups. Mean pain scores were significantly reduced in the intervention group at 3 (3.1 vs 1.1 p < 0.001) and 6 h (4.1 vs 1.7 p < 0.001) at rest and on coughing at 3 (4.8 vs 2.1 p < 0.001) and 6 h (5.4 vs 3.0 p < 0.001). Patient satisfaction was higher (8.0 vs 6.8 p < 0.001) and rescue analgesic requirements (169.4vs 71.3 p < 0.001) lower in the intervention group.

CONCLUSIONS

This analysis has demonstrated the therapeutic benefit of laparoscopic-assisted TAP block in initial post-operative pain management for patients undergoing elective laparoscopic inguinal hernia repair.

摘要

目的

腹腔镜腹股沟疝修补术有助于患者早期活动。在这些日间手术中,术后疼痛的管理至关重要。本研究的目的是比较腹腔镜辅助腹横肌平面(TAP)阻滞与门静脉周围局部麻醉药浸润在术后疼痛管理中的效果。

方法

对2016年1月至2017年10月接受择期腹腔镜腹股沟疝修补术的患者进行了一项双盲随机对照试验。干预组接受30ml 0.25%布比卡因的腹腔镜辅助TAP阻滞。对照组在门静脉周围部位注射15ml 0.5%布比卡因。主要结局指标是使用视觉模拟量表(VAS)的数字评分法评估静息时和咳嗽时3小时的术后疼痛评分。TAP阻滞的疗效通过VAS评估平均疼痛评分降低2分来衡量。

结果

共纳入60例患者(57例男性,3例女性);每组随机分配30例患者。两组患者的人口统计学、麻醉和手术时间相似。干预组静息时和咳嗽时3小时(3.1对1.1,p<0.001)和6小时(4.1对1.7,p<0.001)以及咳嗽时3小时(4.8对2.1,p<0.001)和6小时(5.4对3.0,p<0.001)的平均疼痛评分显著降低。干预组患者满意度更高(8.0对6.8,p<0.001),急救镇痛需求更低(169.4对71.3,p<0.001)。

结论

本分析表明,腹腔镜辅助TAP阻滞在择期腹腔镜腹股沟疝修补术患者术后早期疼痛管理中具有治疗益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2a9/6153948/ef8af18ee3ee/10029_2018_1819_Fig1_HTML.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验