Huret J L, Tanzer J, Henry-Amar M
Hum Genet. 1986 Dec;74(4):447-8. doi: 10.1007/BF00280504.
Three hundred and twenty-five aberrant breakpoints in chronic myelogenous leukaemia (CML) with Philadelphia chromosome variant were reviewed. Eight chromosomal bands (3p21, 6p21, 7p22, 11q13, 12p13, 17p13, 17q21, and 17q25) were found to be highly involved. Apart from 17q25, all these bands correspond to oncogenes sites and/or sites involved as primary breakpoints in cancer.
对325个具有费城染色体变异的慢性粒细胞白血病（CML）异常断点进行了回顾。发现8个染色体带（3p21、6p21、7p22、11q13、12p13、17p13、17q21和17q25）高度受累。除17q25外，所有这些带均对应癌基因位点和/或作为癌症主要断点所涉及的位点。
