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评估积极从事儿童和青少年精神病学实践的社区从业者诊断和治疗 DSM-5 轻度精神病综合征的倾向。

Evaluating the tendencies of community practitioners who actively practice in child and adolescent psychiatry to diagnose and treat DSM-5 attenuated psychotic syndrome.

机构信息

Department of Child and Adolescent Psychiatry, Ankara City Hospital, Üniversiteler, Bilkent Blv. No: 1, Çankaya, 06800, Ankara, Turkey.

Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

出版信息

Eur Child Adolesc Psychiatry. 2022 Oct;31(10):1635-1644. doi: 10.1007/s00787-021-01897-1. Epub 2021 Oct 20.

Abstract

The detection of individuals at clinical ultra-high risk for psychosis (CHR-P) may be a key limiting step for early interventions, and there is some uncertainty regarding the true clinical reliability of the CHR-P states. The aim of this study was to explore how practitioners who were in the direct treatment of children with psychiatric disorders [child psychiatry specialists/trainees (n = 227, n = 131), adult psychiatrists (n = 27), and child neurologists (n = 2)] perceive the DSM-5-Attenuated Psychosis Syndrome (DSM-5-APS), and their clinical routine practice in the treatment of it. Three vignettes describing fictional cases presented with symptoms of either DSM-5-Schizophrenia, DSM-5-APS, and no psychotic symptoms were created. We asked these practitioners to apply a DSM-5 diagnosis and to choose appropriate treatment(s) for these vignettes. Of the responders, 43% correctly diagnosed the APS vignette, whereas 37.4% mentioned that it had a full-blown psychotic episode. Regarding the therapeutic approach for the APS vignette, 72.1% of all practitioners chose a psychopharmacological intervention and 32% individual psychotherapy. This study showed that the diagnostic inter-rater reliability of the DSM-5-APS among child/adolescent mental health practitioners was consistent with the results from the DSM-5 field trials (Kappa = 0.46). Moreover, almost three in four practitioners endorsed psychopharmacological intervention as a treatment option for the DSM-5-APS case. The lack of evidence of psychopharmacological interventions in CHR-P situations emphasizes that the least harmful interventions should be recommended. Thus, our findings indicated a need for raising awareness regarding the CHR-P paradigm and its treatment as well as the development of solid guidelines that can be implemented in clinical practice.

摘要

个体处于精神病超高风险临床状态(CHR-P)的检测可能是早期干预的关键限制步骤,而 CHR-P 状态的真正临床可靠性存在一些不确定性。本研究旨在探讨直接治疗儿童精神障碍的从业者[儿童精神病学专家/受训者(n=227,n=131)、成人精神病学家(n=27)和儿童神经科医生(n=2)]如何看待 DSM-5-缓和性精神病综合征(DSM-5-APS),以及他们在治疗该病时的临床常规实践。我们创建了三个描述虚构病例的情景,这些病例表现出 DSM-5-精神分裂症、DSM-5-APS 和无精神病症状。我们要求这些从业者对这些病例进行 DSM-5 诊断,并为这些病例选择合适的治疗方法。在回答问题的从业者中,43%正确诊断了 APS 病例,而 37.4%则提到这是一个全面的精神病发作。关于 APS 病例的治疗方法,所有从业者中有 72.1%选择了精神药理学干预,32%选择了个体心理治疗。本研究表明,儿童/青少年心理健康从业者对 DSM-5-APS 的诊断组内可靠性与 DSM-5 现场试验的结果一致(Kappa=0.46)。此外,近四分之三的从业者将精神药理学干预作为 DSM-5-APS 病例的治疗选择之一。CHR-P 情况下缺乏精神药理学干预的证据强调,应该推荐危害最小的干预措施。因此,我们的研究结果表明,需要提高对 CHR-P 范式及其治疗的认识,并制定可在临床实践中实施的坚实指南。

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