Mueller Charles, Jonnalagadda Satya, Torres Krysmaru Araujo, Blackmer Allison, Cetnarowski Wes, Chen Yimin, Citty Sandra Wolfe, Dye Elizabeth, Hubbard Van S, Kumbhat Seema, Ottery Faith, Russell Mary E, Sacks Gordon S, Turner Justine
Department of Nutrition, Food Studies and Public Health, New York University, New York, New York, USA.
Westerville, OH.
JPEN J Parenter Enteral Nutr. 2021 Nov;45(8):1619-1626. doi: 10.1002/jpen.2239. Epub 2021 Oct 20.
Parenteral and enteral nutrition support are key components of care for various medical and physiological conditions in infants, children, and adults. Nutrition support practices have advanced over time, driven by the goals of safe and sufficient delivery of needed nutrients and improved patient outcomes. These advances have been, and continue to be, dependent on research and development studies. Such studies address aspects of enteral and parenteral nutrition support: formulations, delivery devices, health outcomes, cost-effectiveness, and related metabolism. The studies are supported by public funding from the government and by private funding from foundations and from the nutrition support industry. To build public trust in nutrition support research findings, it is important to underscore ethical research conduct and reporting of results for all studies, including those with industry sponsors. In 2019, American Society for Parenteral and Enteral Nutrition's (ASPEN's) Board of Directors established a task force to ensure integrity in nutrition support research that is done as collaborative partnerships between the public (government and individuals) and private groups (foundations, academia, and industry). In this ASPEN Position Paper, the Task Force presents principles of ethical research to guide administrators, researchers, and funders. The Task Force identifies ways to curtail bias and to minimize actual or perceived conflict of interests, as related to funding sources and research conduct. Notably, this paper includes a Position Statement to describe the Task Force's guidance on Public-Private Partnerships for research and funding. This paper has been approved by the ASPEN Board of Directors.
肠外营养支持和肠内营养支持是婴儿、儿童及成人各种医疗和生理状况护理的关键组成部分。随着时间的推移，营养支持实践不断进步，这是由安全且充足地提供所需营养素以及改善患者预后的目标所推动的。这些进步一直以来并将继续依赖于研发研究。此类研究涉及肠内和肠外营养支持的多个方面：配方、输送装置、健康结局、成本效益以及相关代谢。这些研究得到了政府的公共资金以及基金会和营养支持行业的私人资金支持。为了建立公众对营养支持研究结果的信任，强调所有研究（包括有行业赞助商的研究）的道德研究行为和结果报告非常重要。2019年，美国肠外和肠内营养学会（ASPEN）董事会成立了一个特别工作组，以确保在公共（政府和个人）与私人团体（基金会、学术界和行业）之间作为合作伙伴关系开展的营养支持研究的诚信。在这份ASPEN立场文件中，特别工作组提出了道德研究原则，以指导管理人员、研究人员和资助者。特别工作组确定了减少偏见以及将与资金来源和研究行为相关的实际或感知利益冲突降至最低的方法。值得注意的是，本文包括一份立场声明，以描述特别工作组对研究和资助公私伙伴关系的指导意见。本文已获ASPEN董事会批准。
