Li Nan, Gui Yizhen, Chu Mengqi, You Mengdi, Qiu Xiaohan, Liu Hejia, Wang Shiang, Deng Meng, Ji Baoming
Henan Key Laboratory of Function-Oriented Porous Materials, College of Chemistry and Chemical Engineering, Luoyang Normal University, Luoyang, Henan 471934, People's Republic of China.
Luoyang Key Laboratory of Organic Functional Molecules, College of Food and Drug, Luoyang Normal University, Luoyang, Henan 471934, People's Republic of China.
Org Lett. 2021 Nov 5;23(21):8460-8464. doi: 10.1021/acs.orglett.1c03185. Epub 2021 Oct 20.
A brief, efficient method has been developed for the removal of the allyl protecting group from allyl carboxylic esters using a Co(II)/TBHP/(MeSiH)O catalytic system. This facile strategy displays excellent chemoselectivity, functional group tolerance, and high yields. This transformation probably occurs through the hydrogen atom transfer process, and a Co(III)-six-membered cyclic intermediate is recommended.
已经开发出一种简短、高效的方法，用于使用Co(II)/叔丁基过氧化氢/（甲基硅氢）氧催化体系从烯丙基羧酸酯中去除烯丙基保护基团。这种简便的策略具有出色的化学选择性、官能团耐受性和高收率。这种转化可能通过氢原子转移过程发生，并推荐一种Co(III)六元环中间体。
