Wiredu Courteney, Haynes Norrisa, Guerra Carmen, Ky Bonnie
Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States.
Division of Cardiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States.
Thromb Haemost. 2022 May;122(5):662-665. doi: 10.1055/a-1674-0259. Epub 2022 Jan 20.
Active malignancy increases the risk of developing venous thromboembolism (VTE) by four- to seven-fold. The risk of VTE, including deep vein thrombosis and pulmonary embolism, in patients with cancer varies based on several clinical factors, such as cancer stage and age. However, race and ethnicity are also associated with increased VTE risk. Black (African American) patients with cancer have a higher risk of developing VTE than White patients, while Asian/Pacific Islanders have a lower risk. Studies on cancer-associated thrombosis demonstrate a need to advance our understanding of both the biologic and sociologic underpinnings of the observed differences according to race. Addressing the causes of these disparities can better health outcomes for historically underserved patient populations.
活动性恶性肿瘤会使发生静脉血栓栓塞（VTE）的风险增加4至7倍。癌症患者发生VTE（包括深静脉血栓形成和肺栓塞）的风险因多种临床因素而异，如癌症分期和年龄。然而，种族和族裔也与VTE风险增加有关。患有癌症的黑人（非裔美国人）患者发生VTE的风险高于白人患者，而亚裔/太平洋岛民的风险较低。关于癌症相关血栓形成的研究表明，有必要加深我们对观察到的种族差异的生物学和社会学基础的理解。解决这些差异的原因可以改善历史上服务不足的患者群体的健康结局。
