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碘造影剂致甲状腺功能亢进症严重并发症心力衰竭 1 例报告。

Heart failure as a serious complication of iodinated contrast-induced hyperthyroidism: case-report.

机构信息

Department of Geriatrics, Tergooi Medical Centre, Blaricum, The Netherlands.

Department of Geriatrics, University Medical Centre Utrecht, Heidelberglaan 8, 3584 CS, Utrecht, The Netherlands.

出版信息

BMC Endocr Disord. 2021 Oct 20;21(1):207. doi: 10.1186/s12902-021-00870-y.

Abstract

BACKGROUND

exposure to iodinated contrast media (ICM) can cause hyperthyroidism, due to disruption of thyroid hormone regulation. Although rare, it can have severe consequences and can lead to fatal complications. Current guidelines do not recommend standard laboratory testing of the thyroid function prior to ICM exposure. Prophylactic treatment of patients at higher risk of hyperthyroidism is not advised.

CASE PRESENTATION

we report the case of an 82-year-old woman who developed ICM induced hyperthyroidism after undergoing a chest computed tomography (CT). One month after ICM administration she presented with pneumonia at the emergency department. Hyperthyroidism was found with concomitant tachycardia, which was hard to control. As a result of hyperthyroidism and coincidental pneumonia the patient developed heart failure and died of myocardial ischemia.

CONCLUSIONS

this case report underlines the importance of close monitoring of high-risk patients after ICM exposure. Clinicians should be aware of the risk of hyperthyroidism and potential severe complications. The use of ICM needs careful consideration, especially in the elderly who suffer more often from multinodular goitre.

摘要

背景

接触碘造影剂(ICM)可因扰乱甲状腺激素调节而导致甲状腺功能亢进,尽管罕见,但可能产生严重后果,并导致致命并发症。目前的指南不建议在接触 ICM 之前对甲状腺功能进行标准实验室检测。也不建议对发生甲状腺功能亢进风险较高的患者进行预防性治疗。

病例介绍

我们报告了一例 82 岁女性患者,她在接受胸部计算机断层扫描(CT)后发生 ICM 诱导的甲状腺功能亢进。在 ICM 给药后一个月,她因肺炎在急诊就诊。检查发现甲状腺功能亢进,同时伴有心动过速,难以控制。由于甲状腺功能亢进和并发肺炎,患者发生心力衰竭并死于心肌缺血。

结论

本病例报告强调了在接触 ICM 后对高危患者进行密切监测的重要性。临床医生应意识到甲状腺功能亢进和潜在严重并发症的风险。需要仔细考虑使用 ICM,特别是在更常患有多结节性甲状腺肿的老年人中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a27e/8527761/ab83eb5d9192/12902_2021_870_Fig1_HTML.jpg

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