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脉冲磁场对烧伤创面的愈合作用。

The healing effect of pulsed magnetic field on burn wounds.

作者信息

Tabakan Ibrahim, Yuvacı Ahmet Umut, Taştekin Bora, Öcal Işıl, Pelit Aykut

机构信息

Department of Plastic, Reconstructive and Aesthetic Surgery, Cukurova University, Medical School, Turkey.

Department of Biophysics, Cukurova University, Medical School, Turkey.

出版信息

Burns. 2022 May;48(3):649-653. doi: 10.1016/j.burns.2021.06.001. Epub 2021 Jun 12.


DOI:10.1016/j.burns.2021.06.001
PMID:34670708
Abstract

A burn is one of the most difficult injuries people can face.The primary pathology is coagulation necrosis resulting from tissue damage.Many wound care products have been developed to be used in situations such as the poor general condition of the patient and lack of solid area to be grafted. However, the high costs of these products make their use complicated.In this study, the effect of PEMF on cutaneous wound healing in an animal burn model was evaluated and the dose and duration of the magnetic field should be discussed for this effect to occur. Animals were divided into five groups including eight each (n = 40) (Groups 1, 2, 3, 4, 5).Group 1 was the control group; received no treatment after second-degree burn wound. Group 2 received daily wound care with saline. Group 3 received daily wound care with pomade containing mupirocin. Group 4 received Pulsed Electromagnetic Field signal for 60 min (1.5 m T and 40 Hz for seven days and Group 5 also received PEMF signal for 60 min the same frequency and intensity for14 days. Microscopically, second-degree burn wounds were successfully detected in all rats. Histopathological examination results in no significant difference between groups in neutrophil infiltration. The difference between the groups in vascularization was statistically significant between Group II and Group V (p < 0.001) and between Group I and Group V (p = 0.005) Epithelialization was present in 75% of the rats in Group V, while no epithelialization was observed in any of the other groups. In conclusion, we observed a significant improvement in the stasis zone of the group receiving Pulsed Electromagnetic Field for two weeks.

摘要

烧伤是人们可能面临的最严重的损伤之一。其主要病理变化是组织损伤导致的凝固性坏死。已经研发出许多伤口护理产品,用于患者一般状况较差以及缺乏可供移植的坚实区域等情况。然而,这些产品的高昂成本使得其使用变得复杂。在本研究中,评估了脉冲电磁场(PEMF)对动物烧伤模型皮肤伤口愈合的影响,并探讨了产生这种影响所需的磁场剂量和持续时间。将动物分为五组,每组八只(n = 40)(第1、2、3、4、5组)。第1组为对照组,二度烧伤伤口后不进行治疗。第2组每天用生理盐水进行伤口护理。第3组每天用含莫匹罗星的软膏进行伤口护理。第4组接受60分钟的脉冲电磁场信号(1.5 mT和40 Hz,持续七天),第5组也接受相同频率和强度的脉冲电磁场信号60分钟,持续14天。显微镜下,在所有大鼠中均成功检测到二度烧伤伤口。组织病理学检查结果显示,各组在中性粒细胞浸润方面无显著差异。在血管形成方面,第2组和第5组之间(p < 0.001)以及第1组和第5组之间(p = 0.005)存在统计学显著差异。第5组75%的大鼠出现上皮化,而其他组均未观察到上皮化。总之,我们观察到接受两周脉冲电磁场治疗的组的淤滞区有显著改善。

相似文献

[1]
The healing effect of pulsed magnetic field on burn wounds.

Burns. 2022-5

[2]
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[3]
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[4]
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[5]
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[6]
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[10]
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引用本文的文献

[1]
Smartphone administered pulsed radio frequency energy therapy for expedited cutaneous wound healing.

NPJ Digit Med. 2025-2-15

[2]
Pulsed electromagnetic fields (PEMF) as a valid tool in orthognathic surgery to reduce post-operative pain and swelling: a prospective study.

Oral Maxillofac Surg. 2024-9

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