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预测单纯三尖瓣手术后结局的风险评分比较。

Comparison of risk scores for predicting outcomes after isolated tricuspid valve surgery.

作者信息

Wang Tom Kai Ming, Akyuz Kevser, Kirincich Jason, Duran Crane Alejandro, Mentias Amgad, Xu Bo, Gillinov A Marc, Pettersson Gosta B, Griffin Brian P, Desai Milind Y

机构信息

Section of Cardiovascular Imaging, Department of Cardiovascular Medicine, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.

Department of Thoracic and Cardiovascular Surgery, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA.

出版信息

J Card Surg. 2022 Jan;37(1):126-134. doi: 10.1111/jocs.16098. Epub 2021 Oct 20.

Abstract

BACKGROUND

Risk models play important roles in stratification and decision-making towards cardiac surgery. Isolated tricuspid valve surgery is a high risk but increasingly performed the operation, however, the performance of risk models has not been externally evaluated in these patients. We compared the prognostic utility of contemporary risk scores for isolated tricuspid valve surgery.

METHODS

Consecutive patients undergoing isolated tricuspid valve surgery at Cleveland Clinic during 2004-2018 were evaluated in this cohort study. EuroSCORE II, Society of Thoracic Surgeon's tricuspid (STS-TVS) score, and the Model for End-stage Liver Disease (MELD) score were retrospectively calculated, and their performance for predicting operative mortality, postoperative complications, and mortality during follow-up was assessed.

RESULTS

Amongst 207 patients studied, the mean age was 54.1 ± 17.9 years, 116 (56.0%) were female, 92 (44.4%) had secondary tricuspid regurgitation, and 151 (72.9%) had a surgical repair. Mean EuroSCORE II, STS-TVS, and MELD scores were 6.3 ± 6.6%, 5.5 ± 6.2%, and 9.8 ± 4.7, respectively. C-statistics (95% confidence intervals) for operative mortality were 0.83 (0.74-0.93) for EuroSCORE II, 0.60 (0.45-0.75) for STS-TVS score, and 0.74 (0.58-0.89) for MELD score, while observed/expected ratios were 0.78 and 0.89 for the first two scores. All three scores were associated with mortality during follow-up and discriminated most postoperative complications.

CONCLUSION

EuroSCORE II was superior to STS-tricuspid score for isolated TVS risk assessment. Although surgical risk scores traditionally underestimated operative mortality after isolated tricuspid valve surgery, they did not in our cohort, reflecting the excellent surgical results. The simple MELD score performed similarly to the EuroSCORE II, especially for discriminating morbidities.

摘要

背景

风险模型在心脏手术的分层和决策中发挥着重要作用。单纯三尖瓣手术风险较高,但此类手术的开展越来越多,然而,风险模型在这些患者中的表现尚未得到外部评估。我们比较了当代风险评分对单纯三尖瓣手术的预后效用。

方法

在这项队列研究中,对2004年至2018年期间在克利夫兰诊所接受单纯三尖瓣手术的连续患者进行了评估。回顾性计算欧洲心脏手术风险评估系统(EuroSCORE)II、胸外科医师协会三尖瓣(STS-TVS)评分和终末期肝病模型(MELD)评分,并评估它们预测手术死亡率、术后并发症及随访期间死亡率的表现。

结果

在研究的207例患者中,平均年龄为54.1±17.9岁,116例(56.0%)为女性,92例(44.4%)有继发性三尖瓣反流,151例(72.9%)接受了手术修复。EuroSCORE II、STS-TVS和MELD评分的平均值分别为6.3±6.6%、5.5±6.2%和9.8±4.7。EuroSCORE II对手术死亡率的C统计量(95%置信区间)为0.83(0.74 - 0.93),STS-TVS评分为0.60(0.45 - 0.75),MELD评分为0.74(0.58 - 0.89),而前两个评分的观察/预期比值分别为0.78和0.89。所有三个评分均与随访期间的死亡率相关,并能区分大多数术后并发症。

结论

在单纯三尖瓣手术风险评估方面,EuroSCORE II优于STS-三尖瓣评分。尽管手术风险评分传统上低估了单纯三尖瓣手术后的手术死亡率,但在我们的队列中并非如此,这反映了出色的手术结果。简单的MELD评分与EuroSCORE II表现相似,尤其是在区分疾病方面。

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