Department of Preventive Medicine, School of Health Sciences, Wuhan University, Wuhan, PR China.
Crit Rev Anal Chem. 2023;53(4):887-905. doi: 10.1080/10408347.2021.1991263. Epub 2021 Oct 21.
Food and human biological samples analysis are of great importance for human health. However, due to the complexity of sample matrices and low concentrations of target analytes, sample preparation is essentially critical for these samples through the whole analytical workflow. Metal-organic frameworks (MOFs), a class of synthesized functional nanomaterial, have been well recognized as novel adsorbents to enhance the sensitivity of current analytical methods and greatly assist the determination of potentially harmful substances present in food and biological samples. This critical review summarized the most advances in the applications of MOFs or hybrid MOFs as adsorbents for food and biological analysis in the past five years, particularly pertaining to sample preparation purpose including removal, adsorption, and enrichment of environmental contaminants. The synthetic routes and analytical performance of representative MOFs or MOFs composites are discussed. The limitations in preparation and application of reported MOFs adsorbents are discussed and the improvement methods for these limitations also have been concluded in the future perspectives.
食品和人体生物样本分析对于人类健康至关重要。然而，由于样本基质的复杂性和目标分析物的低浓度，通过整个分析工作流程，样品制备对于这些样本来说本质上是至关重要的。金属-有机骨架（MOFs）作为一类合成功能纳米材料，已被公认为新型吸附剂，可提高现有分析方法的灵敏度，并极大地帮助检测食品和生物样本中存在的潜在有害物质。本综述总结了过去五年中 MOFs 或杂化 MOFs 作为吸附剂在食品和生物分析中的最新应用进展，特别是在样品制备方面，包括环境污染物的去除、吸附和富集。讨论了代表性 MOFs 或 MOFs 复合材料的合成路线和分析性能。讨论了报道的 MOFs 吸附剂在制备和应用方面的局限性，并在未来展望中总结了改进这些局限性的方法。
