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[Merkel-cell tumor associated with a spinocelluar epithelioma. Apropos a case report].

作者信息

Auriol M, Diner P, Degois G, Boisnic S, Chomette G

出版信息

Rev Stomatol Chir Maxillofac. 1986;87(5):276-81.

PMID:3467405
Abstract

One case of Merkel cell carcinoma is reported in a 71 years-old woman. Lately treated by surgical excision (14 years after the occurrence of the tumour), this tumour was already associated with inguinal lymph node metastases. Its evolution was lethal within 3 months after local recurrence, cutaneous and visceral (lung, liver) metastases. This tumour, characteristic histologically and ultrastructurally (secretory granules), was accompanied by an infiltrative epidermoid carcinoma. This association and the presence of cytokeratin in tumoral Merkel cells are arguments for the common origin of keratinocytes and neuroendocrine Merkel cells from a common young epithelial cell.

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