Sudanese A, Toni A, Baldini N
Tumori. 1986 Oct 31;72(5):535-7. doi: 10.1177/030089168607200516.
A case of osteosarcoma of the distal femur 13 years after the occurrence of a unilateral nonhereditary retinoblastoma is reported. The karyotype of circulating lymphocytis was found to be normal. The existence of a linkage between the two neoplasms due to a subtle chromosomal abnormality is discussed.
报告了1例单侧非遗传性视网膜母细胞瘤发生13年后出现股骨远端骨肉瘤的病例。发现循环淋巴细胞的核型正常。讨论了由于细微染色体异常导致这两种肿瘤之间存在联系的情况。