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2011 - 2018年特立尼达和多巴哥一家初级保健门诊机构的八年抗生素消费情况:消费趋势概述

Eight years of antibiotic consumption at a primary care outpatient facility in Trinidad and Tobago 2011-18: a synopsis of consumption trends.

作者信息

Khan Raveed, Gangar Misty, Gangar Melanie, Motilal Shastri

机构信息

Department of Paraclinical Sciences, The University of the West Indies, St Augustine, Trinidad and Tobago.

Tallahassee Memorial Healthcare, Tallahassee, FL, USA.

出版信息

JAC Antimicrob Resist. 2021 Oct 20;3(4):dlab162. doi: 10.1093/jacamr/dlab162. eCollection 2021 Dec.

Abstract

OBJECTIVES

To explore antibiotic consumption and surveillance patterns in Trinidad and Tobago.

METHODS

A retrospective observational study was conducted. Stock requisition and logbooks from a District Health Facility in Trinidad were examined for the period 2011-18. Daily Defined Doses (DDDs) for each antibiotic were computed and extrapolated to represent the antibiotic consumption per 1000 residents within the population.

RESULTS

The mean consumption across the years was 2.917 DDD per 1000 residents per day. The most consumed antibiotics were cefuroxime, amoxicillin/clavulanic acid, and azithromycin, with mean DDDs of 0.879, 0.695 and 0.373 respectively. The least consumed antibiotics were cefaclor and clarithromycin, with DDDs of 0.0006 and 0.0005, respectively.

CONCLUSIONS

Trinidad and Tobago is not mentioned in the WHO surveillance report on antibiotic consumption. Our most recent (2018) estimate of total antibiotic consumption was 3.224 DDD per 1000 habitants per day. This figure is an underestimate, as data was derived solely from the public sector. Notwithstanding, this data is novel and can provide a baseline for future comparison and development of national surveillance programmes.

摘要

目的

探讨特立尼达和多巴哥的抗生素使用情况及监测模式。

方法

进行了一项回顾性观察研究。对特立尼达一家地区卫生机构2011 - 2018年期间的库存申领单和日志进行了检查。计算每种抗生素的每日限定剂量(DDD),并进行外推以代表每1000名居民中的抗生素消费量。

结果

多年来的平均消费量为每1000名居民每天2.917 DDD。使用最多的抗生素是头孢呋辛、阿莫西林/克拉维酸和阿奇霉素,平均DDD分别为0.879、0.695和0.373。使用最少的抗生素是头孢克洛和克拉霉素,DDD分别为0.0006和0.0005。

结论

世界卫生组织关于抗生素消费的监测报告中未提及特立尼达和多巴哥。我们最近(2018年)对总抗生素消费量的估计是每1000名居民每天3.224 DDD。由于数据仅来自公共部门,这个数字是低估的。尽管如此,这些数据是新的,可为未来国家监测计划的比较和发展提供基线。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89f7/8527501/d9f2df776181/dlab162f1.jpg

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