Division of Clinical Epidemiology, Research Center for Medical Sciences, The Jikei University School of Medicine, Tokyo, Japan.
Department of Nephrology, Saku Central Hospital, Nagano, Japan.
Medicine (Baltimore). 2021 Oct 22;100(42):e27406. doi: 10.1097/MD.0000000000027406.
The transtheoretical model (TTM) is a promising approach to the promotion of behavior change, but it remains to be established whether there is an association between the TTM approach and intradialytic exercise among patients on hemodialysis (HD) with low motivation to exercise in a real-world setting.This retrospective cohort study, conducted in a regional hospital in Japan, included adult outpatients receiving HD 3 times per week who had never participated in intradialytic pedaling exercise despite the encouragement of the HD personnel. Patients were divided into 2 groups according to HD weekday. Patients undergoing HD on Tuesday, Thursday, and Saturday were encouraged by the HD unit team to exercise during HD based on the TTM (exposure group) and those receiving HD on Monday, Wednesday, and Friday were encouraged to exercise as usual (control group). The primary outcome was sustained intradialytic exercise using a leg ergometer, defined as a total of 72 sessions of 30-minute pedaling exercise (duration of at least 6 months).Overall, 85 patients were included in the analysis (mean age: 67.1 ± 11.9 years, 22% female). Of 33 patients in the exposure group, 10 (30%) maintained intradialytic exercise, compared with 2 of 52 patients (4%) in the control group. Log-binomial regression models with stabilized inverse probability of treatment weighting showed a significant association between the TTM approach and sustained intradialytic exercise (adjusted risk ratio 9.23 [95% confidence interval 2.13-40.00]). There were no exercise-related cardiovascular events.Among patients with low motivation to exercise during HD, use of the TTM approach in clinical practice was associated with sustained intradialytic exercise compared with usual care.
跨理论模型(TTM)是促进行为改变的一种很有前途的方法,但在现实环境中,对于低运动动机的血液透析(HD)患者,TTM 方法与透析中运动之间是否存在关联仍有待确定。本回顾性队列研究在日本一家地区医院进行,纳入了每周接受 3 次 HD 治疗且从未参加过透析中踏车运动的成年门诊患者,尽管 HD 工作人员鼓励他们参加。根据 HD 工作日将患者分为 2 组。接受周二、周四和周六 HD 的患者由 HD 团队根据 TTM 鼓励在 HD 期间运动(暴露组),而接受周一、周三和周五 HD 的患者则按常规鼓励运动(对照组)。主要结局是使用腿部功率计进行持续的透析中运动,定义为总共进行 72 次 30 分钟踏车运动(持续至少 6 个月)。共有 85 例患者纳入分析(平均年龄:67.1±11.9 岁,22%为女性)。在暴露组的 33 例患者中,有 10 例(30%)维持了透析中运动,而对照组的 52 例患者中只有 2 例(4%)维持了透析中运动。采用稳定逆概率治疗加权的对数二项式回归模型显示,TTM 方法与持续的透析中运动之间存在显著关联(调整后的风险比 9.23 [95%置信区间 2.13-40.00])。没有与运动相关的心血管事件。在 HD 期间运动动机较低的患者中,与常规护理相比,在临床实践中使用 TTM 方法与持续的透析中运动相关。