Imamura Keigo, Suzuki Yuta, Yamamoto Shohei, Matsuzawa Ryota, Harada Manae, Yamabe Sachi, Osada Shiwori, Matsunaga Atsuhiko
Department of Rehabilitation Sciences, Kitasato University Graduate School of Medical Sciences, 1-15-1 Kitasato, Sagamihara, Kanagawa, 252-0373, Japan.
Department of Rehabilitation, Sagami Circulatory Organ Clinic, Kanagawa, Japan.
Int Urol Nephrol. 2022 Apr;54(4):907-916. doi: 10.1007/s11255-021-02955-y. Epub 2021 Jul 20.
Decreased physical function and physical activity are associated with adverse outcomes among patients undergoing hemodialysis (HD). Although intradialytic exercise (IDEx) can help improve physical function, few studies have evaluated whether long-term IDEx could improve physical function or physical activity in older HD patients. This study aimed to investigate the effects of intradialytic exercise (IDEx) on physical function and physical activity in older HD patients over a 24-month period.
This retrospective study included clinically stable Japanese HD patients (aged ≥ 60 years) who visited our outpatient clinic. The patients were categorized into the IDEx (underwent IDEx) and non-IDEx (did not undergo IDEx) groups. The IDEx group underwent a 30-40 min low-intensity resistance training for three times/week during the HD period. Baseline, 12-month, and 24-month follow-up assessments were conducted to assess patient characteristics, physical function, and physical activity. Results were compared using generalized estimating equations.
The study included 57 patients with complete follow-up data. Baseline, 12-month, and 24-month follow-up assessments revealed no significant inter-group differences concerning physical function, physical activity, and other measurements.
IDEx was shown to have limited effect on physical function and physical activity among older HD patients in a clinical setting. Future studies are needed to re-evaluate IDEx programs in HD patients by incorporating exercises performed before and after the HD session.
在接受血液透析（HD）的患者中，身体功能和身体活动的下降与不良预后相关。尽管透析期间运动（IDEx）有助于改善身体功能，但很少有研究评估长期IDEx是否能改善老年HD患者的身体功能或身体活动。本研究旨在调查透析期间运动（IDEx）对老年HD患者在24个月期间身体功能和身体活动的影响。
这项回顾性研究纳入了到我们门诊就诊的临床稳定的日本HD患者（年龄≥60岁）。患者被分为IDEx组（进行IDEx）和非IDEx组（未进行IDEx）。IDEx组在HD期间每周进行3次30 - 40分钟的低强度阻力训练。在基线、12个月和24个月随访时进行评估，以评估患者特征、身体功能和身体活动。使用广义估计方程比较结果。
该研究纳入了57例有完整随访数据的患者。基线、12个月和24个月随访评估显示，在身体功能、身体活动和其他测量方面，组间无显著差异。
在临床环境中，IDEx对老年HD患者的身体功能和身体活动的影响有限。未来需要通过纳入HD治疗前后进行的运动来重新评估HD患者的IDEx方案。
