Department of Plant and Soil Sciences, University of Kentucky, N-222C Ag. Science Center North, Lexington, KY 40546, USA.
Toxins (Basel). 2021 Sep 25;13(10):683. doi: 10.3390/toxins13100683.
Central Kentucky horse pastures contain significant populations of tall fescue ( (Schreb.) Dumort) infected with an endophyte ( (Morgan-Jones and Gams) Bacon and Schardl) known to produce several ergot alkaloids, with ergovaline in the highest concentration. While most classes of horses are not adversely affected by average levels of ergovaline in pastures, late term pregnant mares have a low tolerance to ergovaline and the related ergot alkaloids. Endophyte-infected tall fescue has been known to cause prolonged gestation, thickened placenta, dystocia, agalactia, and foal and mare mortality. The University of Kentucky Horse Pasture Evaluation Program utilizes ergovaline and endophyte testing, as well as pasture species composition, to calculate ergovaline in the total diet in broodmare pastures. This data is used to develop detailed management recommendations for individual pastures. Application of these recommendations has led to reduced tall fescue toxicity symptoms on these farms, as well as improved pasture management and improved forage quality and quantity.
肯塔基州中部的马场含有大量受内生真菌((Morgan-Jones 和 Gams)Bacon 和 Schardl)感染的高羊茅((Schreb.)Dumort),这些内生真菌已知会产生几种麦角生物碱,其中麦角炔醇的浓度最高。虽然大多数马科动物不会受到牧场中平均水平的麦角炔醇的不利影响,但妊娠后期的母马对麦角炔醇和相关的麦角生物碱的耐受性较低。已知内生真菌感染的高羊茅会导致妊娠延长、胎盘增厚、难产、无乳以及驹和母马死亡。肯塔基大学马场评估计划利用麦角炔醇和内生真菌检测以及牧场物种组成,来计算繁殖母马牧场总饮食中的麦角炔醇。该数据用于为个别牧场制定详细的管理建议。这些建议的应用减少了这些农场的高羊茅毒性症状,以及改善了牧场管理和提高了饲料质量和数量。