Konovalova Elena, Romanenkova Olga, Zimina Anna, Volkova Valeria, Sermyagin Alexander
L.K. Ernst Federal Research Center for Animal Husbandry, Dubrovitsy 60, Podolsk Municipal District, 142132 Moscow, Russia.
Animals (Basel). 2021 Sep 27;11(10):2810. doi: 10.3390/ani11102810.
The myostatin gene () in cattle has a number of polymorphisms associated with increased muscle mass. The aim of the current study was to determine the haplotype frequencies of and polymorphisms among cattle bred for meat in Russia, using DNA analysis. Using the earlier created test systems based on the AS-PCR and PCR-RFLP methods, six populations of Aberdeen Angus ( = 684), two populations of Limousin ( = 54), one population of Simmental ( = 55), and one population of Belgian Blue ( = 137) belonging to Russian farms were genotyped on and polymorphisms. The animal carriers of the mutant allele of associated with the double-muscling genetic defect were found in one Aberdeen Angus population at a frequency of 2.18%, but were not found in the Limousin and Simmental populations. However, 100% of the Belgian Blue population were heterozygous carriers of . The frequencies of the allele desirable for productivity traits in the Limousin populations were the highest and accounted for 0.97 and 1 in populations one and two, while in the Aberdeen Angus, Simmental, and Belgian Blue populations, these figures were considerably lower at 0.04-0.08, depending on the population. The obtained data show the high genetic potential of Russian beef cattle, and facilitate an improvement in meat productivity by preserving the health of animals.
牛的肌肉生长抑制素基因（）存在许多与肌肉量增加相关的多态性。本研究的目的是通过DNA分析确定俄罗斯肉用牛中该基因和多态性的单倍型频率。利用早期基于AS-PCR和PCR-RFLP方法创建的检测系统，对俄罗斯农场的六个阿伯丁安格斯牛群体（=684）、两个利木赞牛群体（=54）、一个西门塔尔牛群体（=55）和一个比利时蓝牛群体（=137）进行了该基因和多态性的基因分型。在一个阿伯丁安格斯牛群体中发现了与双肌遗传缺陷相关的突变等位基因的动物携带者，频率为2.18%，但在利木赞牛和西门塔尔牛群体中未发现。然而，100%的比利时蓝牛群体是该基因的杂合携带者。利木赞牛群体中对生产性状有利的等位基因频率最高，在群体一和群体二中分别为0.97和1，而在阿伯丁安格斯牛、西门塔尔牛和比利时蓝牛群体中，这些数字根据群体不同在0.04 - 0.08之间，要低得多。获得的数据显示了俄罗斯肉牛的高遗传潜力，并通过保持动物健康促进肉用生产力的提高。
