犊牛被动免疫转移评估的当前诊断方法及可能的改进：文献综述
Current Diagnostic Methods for Assessing Transfer of Passive Immunity in Calves and Possible Improvements: A Literature Review.
作者信息
de Souza Rayanne Soalheiro, Dos Santos Lucas Braga Costa, Melo Isabela Oliveira, Cerqueira Daiane Maria, Dumas Juliana Vieira, Leme Fabiola de Oliveira Paes, Moreira Tiago Facury, Meneses Rodrigo Melo, de Carvalho Antônio Ultimo, Facury-Filho Elias Jorge
机构信息
Department of Veterinary Clinic and Surgery, Veterinary School, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, Brazil.
出版信息
Animals (Basel). 2021 Oct 14;11(10):2963. doi: 10.3390/ani11102963.
Several direct or indirect methods can be used to assess immunoglobulin G (IgG) concentrations in calves, which evaluates the transfer of passive immunity (TPI). Radial immunodiffusion (RID) is the gold standard method to measure serum IgG in bovines. Previous studies have shown that colostrum provides several molecules in addition to immunoglobulins, which play an important role in the passive immunity of the calf. However, no studies have yet determined the level of interference of these components in the immunity, health and survival of calves. In this sense, the objective of this study is to review the methods of evaluation available for the laboratory and field diagnosis of TPI in calves and discuss the main aspects of each technique. Several methods available for TPI evaluation in calves may provide insights into the various components of colostrum involved in passive immunity.
有几种直接或间接的方法可用于评估犊牛体内的免疫球蛋白G（IgG）浓度，以此评估被动免疫转移（TPI）情况。放射免疫扩散法（RID）是测量牛血清IgG的金标准方法。先前的研究表明，初乳除了免疫球蛋白外还提供多种分子，这些分子在犊牛的被动免疫中起着重要作用。然而，尚未有研究确定这些成分对犊牛免疫、健康和存活的干扰程度。从这个意义上讲，本研究的目的是回顾可用于犊牛TPI实验室和现场诊断的评估方法，并讨论每种技术的主要方面。犊牛TPI评估的几种可用方法可能有助于深入了解初乳中参与被动免疫的各种成分。
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