Chang Philip J, Asher Arash, Smith Sean R
Department of Physical Medicine and Rehabilitation, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI 48108, USA.
Cancers (Basel). 2021 Oct 16;13(20):5191. doi: 10.3390/cancers13205191.
Persistent pain following treatment for breast cancer is common and often imprecisely labeled as post-mastectomy pain syndrome (PMPS). PMPS is a disorder with multiple potential underlying causes including intercostobrachial nerve injury, intercostal neuromas, phantom breast pain, and pectoralis minor syndrome. Adding further complexity to the issue are various musculoskeletal pain syndromes including cervical radiculopathy, shoulder impingement syndrome, frozen shoulder, and myofascial pain that may occur concurrently and at times overlap with PMPS. These overlapping pain syndromes may be difficult to separate from one another, but precise diagnosis is essential, as treatment for each pain generator may be distinct. The purpose of this review is to clearly outline different pain sources based on anatomic location that commonly occur following treatment for breast cancer, and to provide tailored and evidence-based recommendations for the evaluation and treatment of each disorder.
乳腺癌治疗后持续疼痛很常见，通常被不准确地归类为乳房切除术后疼痛综合征（PMPS）。PMPS是一种有多种潜在病因的病症，包括肋间臂神经损伤、肋间神经瘤、幻乳痛和胸小肌综合征。各种肌肉骨骼疼痛综合征，如颈椎神经根病、肩部撞击综合征、肩周炎和肌筋膜疼痛，使问题更加复杂，这些综合征可能同时发生，有时与PMPS重叠。这些重叠的疼痛综合征可能难以相互区分，但精确诊断至关重要，因为每种疼痛源的治疗方法可能不同。本综述的目的是根据乳腺癌治疗后常见的解剖位置，清晰地概述不同的疼痛来源，并为每种病症的评估和治疗提供针对性的、基于证据的建议。
